PMID- 2348244
OWN - NLM
STAT- MEDLINE
DCOM- 19900712
LR  - 20161123
IS  - 0161-5505 (Print)
IS  - 0161-5505 (Linking)
VI  - 31
IP  - 6
DP  - 1990 Jun
TI  - Colon transit scintigraphy in health and constipation using oral 
      iodine-131-cellulose.
PG  - 985-9
AB  - The purpose of the study was to assess if a new scintigraphic method for 
      noninvasive assessment of colonic transit could differentiate between subjects 
      with normal bowel transit and those with constipation. Eleven normal subjects and 
      29 constipated patients were given 4 MBq iodine-131-cellulose (131I-cellulose) 
      orally and sequential abdominal scans were performed at 6, 24, 48, 72, and 96 hr 
      from which total and segmental percent retentions were calculated. There were 
      clear differences between the normal subjects and the constipated patients for 
      the total percent retention at all time intervals, on a segmental basis in the 
      right colon at 24 hr, and in all segments at 48 and 72 hr. Three-day urinary 
      excretion of radioiodine was minimal; 2.4% +/- 1.2% (mean +/- s.d.) in 
      constipated patients and 3.1% +/- 0.8% in normals, with approximately 75% 
      occurring in the first day. The use of oral radiotracers in the investigation of 
      constipation appears promising.
FAU - McLean, R G
AU  - McLean RG
AD  - Department of Nuclear Medicine, St. George Hospital, Kogarah, New South Wales, 
      Australia.
FAU - Smart, R C
AU  - Smart RC
FAU - Gaston-Parry, D
AU  - Gaston-Parry D
FAU - Barbagallo, S
AU  - Barbagallo S
FAU - Baker, J
AU  - Baker J
FAU - Lyons, N R
AU  - Lyons NR
FAU - Bruck, C E
AU  - Bruck CE
FAU - King, D W
AU  - King DW
FAU - Lubowski, D Z
AU  - Lubowski DZ
FAU - Talley, N A
AU  - Talley NA
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - J Nucl Med
JT  - Journal of nuclear medicine : official publication, Society of Nuclear Medicine
JID - 0217410
RN  - 0 (Iodine Radioisotopes)
RN  - 9004-34-6 (Cellulose)
SB  - IM
MH  - Administration, Oral
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Cellulose/administration & dosage
MH  - Colon/*diagnostic imaging/physiology/physiopathology
MH  - Constipation/*diagnostic imaging/physiopathology
MH  - Female
MH  - Gastrointestinal Transit/*physiology
MH  - Humans
MH  - Iodine Radioisotopes
MH  - Male
MH  - Middle Aged
MH  - Radionuclide Imaging
EDAT- 1990/06/01 00:00
MHDA- 1990/06/01 00:01
CRDT- 1990/06/01 00:00
PHST- 1990/06/01 00:00 [pubmed]
PHST- 1990/06/01 00:01 [medline]
PHST- 1990/06/01 00:00 [entrez]
PST - ppublish
SO  - J Nucl Med. 1990 Jun;31(6):985-9.