PMID- 23482628
OWN - NLM
STAT- MEDLINE
DCOM- 20141223
LR  - 20220309
IS  - 1749-5024 (Electronic)
IS  - 1749-5016 (Print)
IS  - 1749-5016 (Linking)
VI  - 9
IP  - 5
DP  - 2014 May
TI  - Brains creating stories of selves: the neural basis of autobiographical 
      reasoning.
PG  - 646-52
LID - 10.1093/scan/nst028 [doi]
AB  - Personal identity critically depends on the creation of stories about the self 
      and one's life. The present study investigates the neural substrates of 
      autobiographical reasoning, a process central to the construction of such 
      narratives. During functional magnetic resonance imaging scanning, participants 
      approached a set of personally significant memories in two different ways: in 
      some trials, they remembered the concrete content of the events (autobiographical 
      remembering), whereas in other trials they reflected on the broader meaning and 
      implications of their memories (autobiographical reasoning). Relative to 
      remembering, autobiographical reasoning recruited a left-lateralized network 
      involved in conceptual processing [including the dorsal medial prefrontal cortex 
      (MPFC), inferior frontal gyrus, middle temporal gyrus and angular gyrus]. The 
      ventral MPFC--an area that may function to generate personal/affective 
      meaning--was not consistently engaged during autobiographical reasoning across 
      participants but, interestingly, the activity of this region was modulated by 
      individual differences in interest and willingness to engage in self-reflection. 
      These findings support the notion that autobiographical reasoning and the 
      construction of personal narratives go beyond mere remembering in that they 
      require deriving meaning and value from past experiences.
FAU - D'Argembeau, Arnaud
AU  - D'Argembeau A
AD  - Department of Psychology - Cognition and Behavior, University of Liege, Boulevard 
      du Rectorat 3 (B33), 4000 Liege, Belgium. a.dargembeau@ulg.ac.be.
FAU - Cassol, Helena
AU  - Cassol H
FAU - Phillips, Christophe
AU  - Phillips C
FAU - Balteau, Evelyne
AU  - Balteau E
FAU - Salmon, Eric
AU  - Salmon E
FAU - Van der Linden, Martial
AU  - Van der Linden M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130311
PL  - England
TA  - Soc Cogn Affect Neurosci
JT  - Social cognitive and affective neuroscience
JID - 101288795
SB  - IM
MH  - Adult
MH  - Brain/*physiology
MH  - Brain Mapping
MH  - Cues
MH  - Female
MH  - Humans
MH  - Individuality
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Memory/*physiology
MH  - Mental Recall/physiology
MH  - Narration
MH  - Neural Pathways/physiology
MH  - Neuropsychological Tests
MH  - *Self Concept
MH  - Thinking/*physiology
MH  - Young Adult
PMC - PMC4014101
OTO - NOTNLM
OT  - autobiographical memory
OT  - autobiographical reasoning
OT  - fMRI
OT  - self-defining memories
OT  - self-reflection
EDAT- 2013/03/14 06:00
MHDA- 2014/12/24 06:00
PMCR- 2015/05/01
CRDT- 2013/03/14 06:00
PHST- 2013/03/14 06:00 [entrez]
PHST- 2013/03/14 06:00 [pubmed]
PHST- 2014/12/24 06:00 [medline]
PHST- 2015/05/01 00:00 [pmc-release]
AID - nst028 [pii]
AID - 10.1093/scan/nst028 [doi]
PST - ppublish
SO  - Soc Cogn Affect Neurosci. 2014 May;9(5):646-52. doi: 10.1093/scan/nst028. Epub 
      2013 Mar 11.