PMID- 23498823
OWN - NLM
STAT- MEDLINE
DCOM- 20130830
LR  - 20211021
IS  - 1873-2623 (Electronic)
IS  - 0041-1345 (Print)
IS  - 0041-1345 (Linking)
VI  - 45
IP  - 2
DP  - 2013 Mar
TI  - Pregnancy-related human leukocyte antigen sensitization leading to cardiac 
      allograft vasculopathy and graft failure in a heart transplant recipient: a case 
      report.
PG  - 800-2
LID - S0041-1345(12)01330-9 [pii]
LID - 10.1016/j.transproceed.2012.10.038 [doi]
AB  - In this report, we present a heart transplant recipient who developed 
      cross-reactive paternal and donor-specific human leukocyte antigen (HLA) class II 
      antibodies during pregnancy, leading to accelerated cardiac allograft 
      vasculopathy and severe allograft dysfunction 17 years after transplantation. 
      This resulted in acute heart failure and ventricular arrhythmias requiring repeat 
      heart transplantation.
CI  - Copyright (c) 2013 Elsevier Inc. All rights reserved.
FAU - Ginwalla, M
AU  - Ginwalla M
AD  - Division of Cardiovascular Medicine, Stanford University School of Medicine, 
      Stanford, California 94305, USA.
FAU - Pando, M J
AU  - Pando MJ
FAU - Khush, K K
AU  - Khush KK
LA  - eng
GR  - K23 HL091143/HL/NHLBI NIH HHS/United States
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
RN  - 0 (HLA Antigens)
RN  - 0 (Immunosuppressive Agents)
RN  - 0 (Isoantibodies)
SB  - IM
MH  - Adult
MH  - Arrhythmias, Cardiac/immunology
MH  - Cardiomyopathies/*surgery
MH  - Coronary Angiography
MH  - Coronary Artery Disease/diagnosis/*immunology/surgery
MH  - Cross Reactions
MH  - Female
MH  - Graft Rejection/diagnosis/*immunology/surgery
MH  - HLA Antigens/*immunology
MH  - Heart Failure/immunology
MH  - Heart Transplantation/adverse effects/*immunology
MH  - Histocompatibility
MH  - Histocompatibility Testing
MH  - Humans
MH  - Immunosuppressive Agents/therapeutic use
MH  - Isoantibodies/*blood
MH  - Pregnancy
MH  - Reoperation
MH  - Time Factors
MH  - Treatment Outcome
PMC - PMC4451164
MID - NIHMS695147
EDAT- 2013/03/19 06:00
MHDA- 2013/08/31 06:00
PMCR- 2015/06/02
CRDT- 2013/03/19 06:00
PHST- 2012/06/30 00:00 [received]
PHST- 2012/10/08 00:00 [revised]
PHST- 2012/10/16 00:00 [accepted]
PHST- 2013/03/19 06:00 [entrez]
PHST- 2013/03/19 06:00 [pubmed]
PHST- 2013/08/31 06:00 [medline]
PHST- 2015/06/02 00:00 [pmc-release]
AID - S0041-1345(12)01330-9 [pii]
AID - 10.1016/j.transproceed.2012.10.038 [doi]
PST - ppublish
SO  - Transplant Proc. 2013 Mar;45(2):800-2. doi: 10.1016/j.transproceed.2012.10.038.