PMID- 23507331 OWN - NLM STAT- MEDLINE DCOM- 20140211 LR - 20220331 IS - 1872-6844 (Electronic) IS - 0920-1211 (Linking) VI - 105 IP - 1-2 DP - 2013 Jul TI - Prevalence of epilepsy in the People's Republic of China: a systematic review. PG - 195-205 LID - S0920-1211(13)00040-5 [pii] LID - 10.1016/j.eplepsyres.2013.02.002 [doi] AB - To date there has not been a nationwide systematic analysis of the prevalence of epilepsy in China. The aim of this study was to estimate the prevalence of epilepsy in mainland China from the published studies and analyze the prevalence of epilepsy by survey method, gender, location, age, seizure type and prevalence of date. We searched the PubMed, Embase, Chinese Biological Medical Literature (CBM), Chinese National Knowledge Infrastructure (CNKI), Chinese Wanfang and Chongqing VIP databases for epidemiological studies on the prevalence of epilepsy. Thirty-eight studies were included that comprised a total sample size of 7,695,961, among whom 13,224 had epilepsy. The overall prevalence of epilepsy was 2.89 per thousand. The prevalence of males and females were 3.83 per thousand and 3.45 per thousand, respectively. The location-specific prevalence in urban and rural areas was 2.34 per thousand and 3.17 per thousand, respectively. Prevalence by age groups, 0-9, 10-19, 20-29, 30-39, 40-49, 50-59, 60-69 and >/=70 were 2.21 per thousand, 3.23 per thousand, 3.14 per thousand, 2.83 per thousand, 2.96 per thousand, 2.61 per thousand, 2.76 per thousand and 2.22 per thousand, respectively. In the subgroup analysis by prevalence date, prevalence rate of epilepsy ranged from 1.19 per thousand to 6.70 per thousand. As for the seizure types, the overall prevalence of generalized seizures, partial seizures and unclassifiable seizures were 3.12 per thousand, 0.57 per thousand and 0.23 per thousand, respectively. Overall, the prevalence rate of epilepsy is different for each area in mainland China. A higher prevalence of epilepsy is found in the subgroup analysis by male, rural, age group of 10-19 and generalized seizures. However, more epidemiological studies are needed from other provinces to estimate the overall prevalence of epilepsy in mainland China. CI - Copyright (c) 2013 Elsevier B.V. All rights reserved. FAU - Gu, Lian AU - Gu L AD - Department of Internal Neurology, First Affiliated Hospital, Guangxi University of Chinese Medicine, Nanning, Guangxi, China. FAU - Liang, Baoyun AU - Liang B FAU - Chen, Qing AU - Chen Q FAU - Long, Jianxiong AU - Long J FAU - Xie, Juanjuan AU - Xie J FAU - Wu, Guangliang AU - Wu G FAU - Yan, Yan AU - Yan Y FAU - Tan, Jinjing AU - Tan J FAU - Dou, Weihua AU - Dou W FAU - Chen, Wei AU - Chen W FAU - Wu, Peng AU - Wu P FAU - Wang, Jinping AU - Wang J FAU - Su, Li AU - Su L LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PT - Systematic Review DEP - 20130316 PL - Netherlands TA - Epilepsy Res JT - Epilepsy research JID - 8703089 SB - IM MH - China/epidemiology MH - Epilepsy/*diagnosis/*epidemiology MH - Humans MH - Prevalence EDAT- 2013/03/20 06:00 MHDA- 2014/02/12 06:00 CRDT- 2013/03/20 06:00 PHST- 2012/09/03 00:00 [received] PHST- 2012/12/13 00:00 [revised] PHST- 2013/02/11 00:00 [accepted] PHST- 2013/03/20 06:00 [entrez] PHST- 2013/03/20 06:00 [pubmed] PHST- 2014/02/12 06:00 [medline] AID - S0920-1211(13)00040-5 [pii] AID - 10.1016/j.eplepsyres.2013.02.002 [doi] PST - ppublish SO - Epilepsy Res. 2013 Jul;105(1-2):195-205. doi: 10.1016/j.eplepsyres.2013.02.002. Epub 2013 Mar 16.