PMID- 23507749
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130320
LR  - 20211021
IS  - 1422-0067 (Print)
IS  - 1422-0067 (Electronic)
IS  - 1422-0067 (Linking)
VI  - 14
IP  - 3
DP  - 2013 Mar 18
TI  - Comparative Analysis of Serum (Anti)oxidative Status Parsmall a, Cyrillicmeters in Healthy 
      Persons.
PG  - 6106-15
LID - 10.3390/ijms14036106 [doi]
AB  - Five antioxidant and two oxidative stress assays were applied to serum samples of 
      43 healthy males. The antioxidant tests showed different inter-assay 
      correlations. A very good correlation of 0.807 was observed between the ferric 
      reducing ability of plasma (FRAP) and total antioxidant status (TAS) assay and 
      also a fair correlation of 0.501 between the biological antioxidant potential 
      (BAP) and TAS assay. There was no statistically significant correlation between 
      the BAP and FRAP assay. The anti-oxidant assays have a high correlation with uric 
      acid, especially the TAS (0.922) and FRAP assay (0.869). The BAP assay has a much 
      lower and no statistically significant correlation with uric acid (0.302), which 
      makes BAP more suitable for the antioxidant status. The total thiol assay showed 
      no statistically significant correlation with uric acid (0.114). The total thiol 
      assay, which is based on a completely different principle, showed a good and 
      statistically significant correlation with the BAP assay (0.510) and also to the 
      TAS assay, but to a lower and not significant extent (0.279) and not with the 
      FRAP assay (-0.008). The oxy-adsorbent test (OXY) assay has no correlation with 
      any of the other assays tested. The oxidative stress assays, reactive oxygen 
      metabolites (ROM) and total oxidant status (TOS), based on a different principle, 
      do not show a statistically significant correlation with the serum samples in 
      this study. Both assays showed a negative, but not significant, correlation with 
      the antioxidant assays. In conclusion, the ROM, TOS, BAP and TTP assays are based 
      on different principles and will have an additional value when a combination of 
      these assays will be applied in large-scale population studies.
FAU - Jansen, Eugene Hjm
AU  - Jansen EH
AD  - Center for Health Protection, National Institute for Public Health and the 
      Environment, Bilthoven, The Netherlands. eugene.jansen@rivm.nl.
FAU - Ruskovska, Tatjana
AU  - Ruskovska T
LA  - eng
PT  - Journal Article
DEP - 20130318
PL  - Switzerland
TA  - Int J Mol Sci
JT  - International journal of molecular sciences
JID - 101092791
PMC - PMC3634506
EDAT- 2013/03/20 06:00
MHDA- 2013/03/20 06:01
PMCR- 2013/03/01
CRDT- 2013/03/20 06:00
PHST- 2012/12/31 00:00 [received]
PHST- 2013/03/05 00:00 [revised]
PHST- 2013/03/07 00:00 [accepted]
PHST- 2013/03/20 06:00 [entrez]
PHST- 2013/03/20 06:00 [pubmed]
PHST- 2013/03/20 06:01 [medline]
PHST- 2013/03/01 00:00 [pmc-release]
AID - ijms14036106 [pii]
AID - ijms-14-06106 [pii]
AID - 10.3390/ijms14036106 [doi]
PST - epublish
SO  - Int J Mol Sci. 2013 Mar 18;14(3):6106-15. doi: 10.3390/ijms14036106.