PMID- 23510596
OWN - NLM
STAT- MEDLINE
DCOM- 20131025
LR  - 20160526
IS  - 1573-2509 (Electronic)
IS  - 0920-9964 (Linking)
VI  - 146
IP  - 1-3
DP  - 2013 May
TI  - Interview-based assessment of cognition in schizophrenia: applicability of the 
      Schizophrenia Cognition Rating Scale (SCoRS) in different phases of illness and 
      settings of care.
PG  - 217-23
LID - S0920-9964(13)00127-8 [pii]
LID - 10.1016/j.schres.2013.02.035 [doi]
AB  - INTRODUCTION: The Schizophrenia Cognition Rating Scale (SCoRS), an 
      interview-based assessment of cognition, has proved to be a valid measure of 
      cognitive performance in patients with schizophrenia. OBJECTIVE: The aims of this 
      study were to analyze the validity of this scale in a naturalistic setting 
      representative of the Italian system of psychiatric care, and to test whether the 
      SCoRS could be appropriately used in different phases of illness and contexts of 
      care. METHODS: Eighty-six patients with schizophrenia (DSM-IV-TR criteria) (N = 
      59 clinically stabilized patients; N = 27 recently hospitalized patients) were 
      administered the SCoRS. The reliability of SCoRS was assessed and global ratings 
      were correlated with neurocognitive, clinical, and psychosocial functioning 
      measures. RESULTS: SCoRS inter-rater and test-retest reliability were high. In 
      clinically stabilized patients, SCoRS global ratings were significantly 
      correlated with composite scores of cognitive performance (global cognitive 
      index: r = -0.570, P<0.001), symptoms (Positive and Negative Syndrome Scale 
      (PANSS) total score: r = 0.602, P < 0.001), and psychosocial functioning (Global 
      Assessment of Functioning (GAF): r = -0.532, P<0.001; Health of the Nation 
      Outcome Scale (HoNOS): r = 0.433, P < 0.001). On the other hand, no such 
      correlations were found in recently hospitalized patients. Correlations with 
      neuropsychological and functional measures were less significant as the severity 
      of the patients' symptoms, especially positive symptoms, increased. CONCLUSION: 
      The SCoRS is a valid measure of cognitive performance and is related to 
      psychosocial functioning, especially in clinically stable patients with 
      schizophrenia. The usefulness of the SCoRS in patients recently admitted to 
      hospital for an acute phase of illness is uncertain.
CI  - Copyright (c) 2013 Elsevier B.V. All rights reserved.
FAU - Vita, Antonio
AU  - Vita A
AD  - University of Brescia, School of Medicine, Brescia, Italy; Department of Mental 
      Health, Spedali Civili Hospital, Brescia, Italy. vita.dsm@libero.it
FAU - Deste, Giacomo
AU  - Deste G
FAU - Barlati, Stefano
AU  - Barlati S
FAU - De Peri, Luca
AU  - De Peri L
FAU - Giambra, Agnese
AU  - Giambra A
FAU - Poli, Roberto
AU  - Poli R
FAU - Keefe, Richard S E
AU  - Keefe RS
FAU - Sacchetti, Emilio
AU  - Sacchetti E
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130317
PL  - Netherlands
TA  - Schizophr Res
JT  - Schizophrenia research
JID - 8804207
SB  - IM
MH  - Adult
MH  - Cognition Disorders/*diagnosis/*etiology
MH  - Disease Progression
MH  - Female
MH  - Humans
MH  - Interview, Psychological/*methods
MH  - Male
MH  - Middle Aged
MH  - Neuropsychological Tests
MH  - Psychiatric Status Rating Scales
MH  - Psychometrics
MH  - Reproducibility of Results
MH  - Schizophrenia/*complications
MH  - *Schizophrenic Psychology
MH  - Statistics as Topic
MH  - Statistics, Nonparametric
EDAT- 2013/03/21 06:00
MHDA- 2013/10/26 06:00
CRDT- 2013/03/21 06:00
PHST- 2012/10/15 00:00 [received]
PHST- 2013/02/17 00:00 [revised]
PHST- 2013/02/24 00:00 [accepted]
PHST- 2013/03/21 06:00 [entrez]
PHST- 2013/03/21 06:00 [pubmed]
PHST- 2013/10/26 06:00 [medline]
AID - S0920-9964(13)00127-8 [pii]
AID - 10.1016/j.schres.2013.02.035 [doi]
PST - ppublish
SO  - Schizophr Res. 2013 May;146(1-3):217-23. doi: 10.1016/j.schres.2013.02.035. Epub 
      2013 Mar 17.