PMID- 23514330
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130730
LR  - 20211021
IS  - 1550-2783 (Print)
IS  - 1550-2783 (Electronic)
IS  - 1550-2783 (Linking)
VI  - 10
IP  - 1
DP  - 2013 Mar 20
TI  - Influence of carbohydrate ingestion on salivary immunoglobulin A following 
      resistance exercise.
PG  - 14
LID - 10.1186/1550-2783-10-14 [doi]
AB  - BACKGROUND: Heavy exercise stresses immune function, however carbohydrate (CHO) 
      supplementation has been shown to attenuate the decline in some measures of 
      immune function after exercise. The purpose of the study was to investigate the 
      impact of CHO supplementation on salivary immunoglobulin A (s-IgA) levels, 
      interleukin 2 (IL-2), and interleukin 5 (IL-5), following an acute bout of 
      resistance exercise (RE). METHODS: Ten resistance trained male collegiate 
      athletes (21+/-2 yr; 174+/-6 cm, 80+/-11kg, 14%+/-4% fat) performed RE consisting of four 
      exercises (leg press, lat pull-downs, bench press, and leg curls). Volunteers 
      performed four sets of 10 repetitions at 65% of 1-RM, with 2 min rest between 
      sets for all exercises. Subjects consumed either CHO beverage (1 g*kg-1 body 
      weight) or placebo (P) prior to, during, and after RE (randomized, double blind 
      design). Saliva and venous blood were collected pre-, post- and 90 min 
      post-exercise. RESULTS: No change occurred in s-IgA from rest relative to 
      osmolality or as a secretion rate (p > 0.05). IL-2 levels were unchanged by 
      exercise in both trials (time effect p = 0.342). IL-5 was significantly (time 
      effect p = 0.04) decreased between rest (1.55 +/- 0.07 pg*ml-1) and 90 min 
      post-exercise (0.96 +/- 0 .11 pg*ml-1), with no difference between treatments 
      (group x time effect p = 0.610). There was no time-by-treatment interaction (p < 
      0.05) observed between CHO and P treatments for s-IgA or IL-5. CONCLUSION: IL-5 
      decreases after RE, but s-IgA and IL-2 levels remain stable. CHO ingestion prior 
      to-, during or following RE did not appear to alter salivary immune responses.
FAU - Carlson, Lara A
AU  - Carlson LA
AD  - University of New England, 11 Hills Beach Road Pickus Biomedical Center #209, 
      Biddeford, ME 04005, USA. lcarlson@une.edu.
FAU - Kenefick, Robert W
AU  - Kenefick RW
FAU - Koch, Alexander J
AU  - Koch AJ
LA  - eng
PT  - Journal Article
DEP - 20130320
PL  - United States
TA  - J Int Soc Sports Nutr
JT  - Journal of the International Society of Sports Nutrition
JID - 101234168
PMC - PMC3726298
EDAT- 2013/03/22 06:00
MHDA- 2013/03/22 06:01
PMCR- 2013/03/20
CRDT- 2013/03/22 06:00
PHST- 2012/12/05 00:00 [received]
PHST- 2013/03/13 00:00 [accepted]
PHST- 2013/03/22 06:00 [entrez]
PHST- 2013/03/22 06:00 [pubmed]
PHST- 2013/03/22 06:01 [medline]
PHST- 2013/03/20 00:00 [pmc-release]
AID - 1550-2783-10-14 [pii]
AID - 10.1186/1550-2783-10-14 [doi]
PST - epublish
SO  - J Int Soc Sports Nutr. 2013 Mar 20;10(1):14. doi: 10.1186/1550-2783-10-14.