PMID- 23515932
OWN - NLM
STAT- MEDLINE
DCOM- 20150207
LR  - 20211021
IS  - 1573-3521 (Electronic)
IS  - 0160-7715 (Print)
IS  - 0160-7715 (Linking)
VI  - 37
IP  - 3
DP  - 2014 Jun
TI  - The differential associations of depression and diabetes distress with quality of 
      life domains in type 2 diabetes.
PG  - 501-10
LID - 10.1007/s10865-013-9505-x [doi]
AB  - The present investigation aimed to understand quality of life domains relevant to 
      adults with type 2 diabetes mellitus (T2DM), and the relative associations of 
      depression and diabetes distress with these domains. Participants were 146 
      individuals with T2DM who were recruited for entry into a randomized controlled 
      trial of cognitive behavioral therapy for adherence and depression. We conducted 
      an exploratory factor analysis on the Quality of Life Inventory (QOLI) to 
      establish domains of quality of life relevant to this patient population. 
      Hierarchical multiple regression models were evaluated for each domain that 
      emerged to determine independent associations of depression severity and diabetes 
      distress with quality of life independent of demographic and illness factors. 
      Results suggested four quality of life domains: achievement, psychosocial growth, 
      interpersonal relationships, and environment, accounting for 60.1 % of variance 
      in total QOLI scores. Depression severity was associated with poorer quality of 
      life on the achievement, psychosocial growth, and environment domains 
      (p's < 0.01), while diabetes distress was associated with poorer quality of life 
      on the achievement (p < 0.001) domain and marginally associated with quality of 
      life on the psychosocial growth (p < 0.10) domain. Interventions designed to 
      address both depression and diabetes distress may lead to better quality of life 
      outcomes than a generalized depression intervention or an intervention for 
      diabetes alone.
FAU - Carper, Matthew M
AU  - Carper MM
AD  - Behavioral Medicine Service, Massachusetts General Hospital, Boston, MA, USA, 
      matthew.carper@temple.edu.
FAU - Traeger, Lara
AU  - Traeger L
FAU - Gonzalez, Jeffrey S
AU  - Gonzalez JS
FAU - Wexler, Deborah J
AU  - Wexler DJ
FAU - Psaros, Christina
AU  - Psaros C
FAU - Safren, Steven A
AU  - Safren SA
LA  - eng
GR  - DK 020541/DK/NIDDK NIH HHS/United States
GR  - K24 MH094214/MH/NIMH NIH HHS/United States
GR  - P30 DK020541/DK/NIDDK NIH HHS/United States
GR  - UL1 RR 025758/RR/NCRR NIH HHS/United States
GR  - R01MH078571/MH/NIMH NIH HHS/United States
GR  - R01 MH078571/MH/NIMH NIH HHS/United States
GR  - UL1 RR025758/RR/NCRR NIH HHS/United States
GR  - P60 DK020541/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20130321
PL  - United States
TA  - J Behav Med
JT  - Journal of behavioral medicine
JID - 7807105
SB  - IM
MH  - Depressive Disorder/*psychology
MH  - Diabetes Mellitus, Type 2/*psychology
MH  - Factor Analysis, Statistical
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Quality of Life/*psychology
MH  - Randomized Controlled Trials as Topic
MH  - Stress, Psychological/*psychology
PMC - PMC3758402
MID - NIHMS458439
EDAT- 2013/03/22 06:00
MHDA- 2015/02/11 06:00
PMCR- 2015/06/01
CRDT- 2013/03/22 06:00
PHST- 2012/07/16 00:00 [received]
PHST- 2013/03/14 00:00 [accepted]
PHST- 2013/03/22 06:00 [entrez]
PHST- 2013/03/22 06:00 [pubmed]
PHST- 2015/02/11 06:00 [medline]
PHST- 2015/06/01 00:00 [pmc-release]
AID - 10.1007/s10865-013-9505-x [doi]
PST - ppublish
SO  - J Behav Med. 2014 Jun;37(3):501-10. doi: 10.1007/s10865-013-9505-x. Epub 2013 Mar 
      21.