PMID- 23516985
OWN - NLM
STAT- MEDLINE
DCOM- 20130626
LR  - 20230207
IS  - 1545-3278 (Electronic)
IS  - 0732-0582 (Print)
IS  - 0732-0582 (Linking)
VI  - 31
DP  - 2013
TI  - The dendritic cell lineage: ontogeny and function of dendritic cells and their 
      subsets in the steady state and the inflamed setting.
PG  - 563-604
LID - 10.1146/annurev-immunol-020711-074950 [doi]
AB  - Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive 
      immune responses according to peripheral cues. After four decades of research, we 
      now know that DCs arise from a hematopoietic lineage distinct from other 
      leukocytes, establishing the DC system as a unique hematopoietic branch. Recent 
      work has also established that tissue DCs consist of developmentally and 
      functionally distinct subsets that differentially regulate T lymphocyte function. 
      This review discusses major advances in our understanding of the regulation of DC 
      lineage commitment, differentiation, diversification, and function in situ.
FAU - Merad, Miriam
AU  - Merad M
AD  - Department of Oncological Sciences, Mount Sinai Medical School, New York, NY 
      10029, USA. Miriam.merad@mssm.edu
FAU - Sathe, Priyanka
AU  - Sathe P
FAU - Helft, Julie
AU  - Helft J
FAU - Miller, Jennifer
AU  - Miller J
FAU - Mortha, Arthur
AU  - Mortha A
LA  - eng
GR  - R01 CA173861/CA/NCI NIH HHS/United States
GR  - U01 AI095611/AI/NIAID NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Annu Rev Immunol
JT  - Annual review of immunology
JID - 8309206
RN  - 0 (Inflammation Mediators)
SB  - IM
MH  - Animals
MH  - Cell Differentiation/*immunology
MH  - Cell Lineage/*immunology
MH  - Cell Movement/immunology
MH  - Dendritic Cells/cytology/*immunology/*pathology
MH  - Humans
MH  - Inflammation/immunology/metabolism/pathology
MH  - Inflammation Mediators/physiology
MH  - Lymphoid Tissue/cytology/immunology/pathology
PMC - PMC3853342
MID - NIHMS495534
EDAT- 2013/03/23 06:00
MHDA- 2013/06/28 06:00
PMCR- 2013/12/06
CRDT- 2013/03/23 06:00
PHST- 2013/03/23 06:00 [entrez]
PHST- 2013/03/23 06:00 [pubmed]
PHST- 2013/06/28 06:00 [medline]
PHST- 2013/12/06 00:00 [pmc-release]
AID - 10.1146/annurev-immunol-020711-074950 [doi]
PST - ppublish
SO  - Annu Rev Immunol. 2013;31:563-604. doi: 10.1146/annurev-immunol-020711-074950.