PMID- 23517460
OWN - NLM
STAT- MEDLINE
DCOM- 20140204
LR  - 20180813
IS  - 1751-7133 (Electronic)
IS  - 1527-5299 (Linking)
VI  - 19
IP  - 4
DP  - 2013 Jul-Aug
TI  - Can vitamin D supplementation improve the severity of congestive heart failure?
PG  - E22-8
LID - 10.1111/chf.12026 [doi]
AB  - The aim of the present study was to investigate whether vitamin D supplementation 
      could improve biochemical findings and functional capacity of patients with heart 
      failure (HF). One hundred patients with New York Heart Association (NYHA) class I 
      through III HF were included in this prospective study and their 
      25-hydroxyvitamin D levels were evaluated. Only 6% of the participants had a 
      sufficient serum concentration of 25(OH) D >30 nmol/L. Patients with insufficient 
      or deficient serum levels of 25(OH) D (<30 ng/mL and <20 ng/mL, respectively) 
      received oral vitamin D3 (cholecalciferol) for a total period of 4 months. 
      Vitamin D supplementation increased mean serum concentration of 25(OH) D from 
      12.63+/-7.60 nmol/L to 54.49+/-18.01 nmol/L (P<.001). After vitamin D 
      supplementation, the serum level of pro-brain natriuretic peptide markedly 
      decreased (P<.001). Cholecalciferol significantly decreased high-sensitivity 
      C-reactive protein level (P<.001). Restoration of serum 25(OH) D level was also 
      associated with substantial improvement in NYHA class (P<.001) and 6-minute walk 
      distance (P<.001).
CI  - (c) 2013 Wiley Periodicals, Inc.
FAU - Amin, Ahmad
AU  - Amin A
AD  - Department of Heart Failure and Transplantation, Fellowship in Heart Failure & 
      Transplantation, Rajaei Cardiovascular, Medical and Research Center, Tehran 
      University of Medical Sciences, Tehran, Iran. amina33@gmail.com
FAU - Minaee, Shima
AU  - Minaee S
FAU - Chitsazan, Mitra
AU  - Chitsazan M
FAU - Naderi, Nassim
AU  - Naderi N
FAU - Taghavi, Sepideh
AU  - Taghavi S
FAU - Ardeshiri, Maryam
AU  - Ardeshiri M
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20130321
PL  - United States
TA  - Congest Heart Fail
JT  - Congestive heart failure (Greenwich, Conn.)
JID - 9714174
RN  - 0 (Vitamins)
RN  - 1406-16-2 (Vitamin D)
RN  - 9007-41-4 (C-Reactive Protein)
RN  - A288AR3C9H (25-hydroxyvitamin D)
SB  - IM
MH  - C-Reactive Protein/metabolism
MH  - *Dietary Supplements
MH  - Disease Progression
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/blood/*drug therapy
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prognosis
MH  - Prospective Studies
MH  - Vitamin D/*administration & dosage/*analogs & derivatives/blood
MH  - Vitamins/administration & dosage
EDAT- 2013/03/23 06:00
MHDA- 2014/02/05 06:00
CRDT- 2013/03/23 06:00
PHST- 2012/06/14 00:00 [received]
PHST- 2013/02/01 00:00 [revised]
PHST- 2013/02/03 00:00 [accepted]
PHST- 2013/03/23 06:00 [entrez]
PHST- 2013/03/23 06:00 [pubmed]
PHST- 2014/02/05 06:00 [medline]
AID - 10.1111/chf.12026 [doi]
PST - ppublish
SO  - Congest Heart Fail. 2013 Jul-Aug;19(4):E22-8. doi: 10.1111/chf.12026. Epub 2013 
      Mar 21.