PMID- 23522019
OWN - NLM
STAT- MEDLINE
DCOM- 20130925
LR  - 20151119
IS  - 1475-097X (Electronic)
IS  - 1475-0961 (Linking)
VI  - 33
IP  - 3
DP  - 2013 May
TI  - Plasma oxidative stress is induced by single-sprint anaerobic exercise in young 
      cigarette smokers.
PG  - 241-4
LID - 10.1111/cpf.12007 [doi]
AB  - Cigarette smoking increases oxidative stress, which is a risk factor for several 
      diseases. Smoking has also been reported to enhance plasma oxidative stress 
      during strenuous exercise. However, no prior study has examined the changes in 
      plasma oxidative stress after single-sprint anaerobic exercise in cigarette 
      smokers. The purpose of this study was to investigate these changes in young 
      cigarette smokers by measuring reactive oxygen species generation and total 
      antioxidant content. Participants were 15 male smokers (mean age: 
      25.9 +/- 2.9 years) and 18 male non-smokers (mean age: 24.2 +/- 4.3 years). 
      Hydroperoxide concentration and biological antioxidant potential (BAP) in plasma 
      were measured at baseline and after the Wingate anaerobic test. A significant 
      interaction between group and time was observed for plasma hydroperoxide 
      concentration (P = 0.037). Plasma hydroperoxide concentration was significantly 
      increased after exercise in both smokers and non-smokers (P = 0.001 and <0.001, 
      respectively). However, no significant interaction was observed between groups by 
      time on plasma BAP (P = 0.574), and a main effect of time was observed (P<0.001). 
      Plasma BAP was significantly increased after exercise in both groups (both, 
      P<0.001). These findings indicate that plasma oxidative stress is higher in 
      cigarette smokers than in non-smokers after single-sprint anaerobic exercise, 
      which may increase the risk of oxidative damage.
CI  - (c) 2012 The Authors Clinical Physiology and Functional Imaging (c) 2012 Scandinavian 
      Society of Clinical Physiology and Nuclear Medicine.
FAU - Taito, Shunsuke
AU  - Taito S
AD  - Department of Health and Sports Medical Sciences, Graduate School of Biomedical 
      and Health Sciences, Hiroshima University, Hiroshima, Japan.
FAU - Sekikawa, Kiyokazu
AU  - Sekikawa K
FAU - Oura, Keisuke
AU  - Oura K
FAU - Kamikawa, Norimichi
AU  - Kamikawa N
FAU - Matsuki, Ryosuke
AU  - Matsuki R
FAU - Kimura, Tatsushi
AU  - Kimura T
FAU - Takahashi, Makoto
AU  - Takahashi M
FAU - Inamizu, Tsutomu
AU  - Inamizu T
FAU - Hamada, Hironobu
AU  - Hamada H
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20121108
PL  - England
TA  - Clin Physiol Funct Imaging
JT  - Clinical physiology and functional imaging
JID - 101137604
RN  - 0 (Antioxidants)
RN  - 0 (Biomarkers)
RN  - BBX060AN9V (Hydrogen Peroxide)
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Antioxidants/metabolism
MH  - Biomarkers/blood
MH  - Case-Control Studies
MH  - *Exercise
MH  - Exercise Test
MH  - Humans
MH  - Hydrogen Peroxide/blood
MH  - Male
MH  - *Oxidative Stress
MH  - Smoking/adverse effects/*blood
MH  - Time Factors
MH  - Young Adult
EDAT- 2013/03/26 06:00
MHDA- 2013/09/26 06:00
CRDT- 2013/03/26 06:00
PHST- 2012/05/20 00:00 [received]
PHST- 2012/10/04 00:00 [accepted]
PHST- 2013/03/26 06:00 [entrez]
PHST- 2013/03/26 06:00 [pubmed]
PHST- 2013/09/26 06:00 [medline]
AID - 10.1111/cpf.12007 [doi]
PST - ppublish
SO  - Clin Physiol Funct Imaging. 2013 May;33(3):241-4. doi: 10.1111/cpf.12007. Epub 
      2012 Nov 8.