PMID- 23522618
OWN - NLM
STAT- MEDLINE
DCOM- 20130715
LR  - 20130408
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1288
DP  - 2013 May 3
TI  - D-optimal experimental design coupled with parallel factor analysis 2 
      decomposition a useful tool in the determination of triazines in oranges by 
      programmed temperature vaporization-gas chromatography-mass spectrometry when 
      using dispersive-solid phase extraction.
PG  - 111-26
LID - S0021-9673(13)00406-8 [pii]
LID - 10.1016/j.chroma.2013.02.088 [doi]
AB  - The determination of triazines in oranges using a GC-MS system coupled to a 
      programmed temperature vaporizer (PTV) inlet in the context of legislation is 
      performed. Both pretreatment (using a Quick Easy Cheap Effective Rugged and Safe 
      (QuEChERS) procedure) and injection steps are optimized using D-optimal 
      experimental designs for reducing the experimental effort. The relative dirty 
      extracts obtained and the elution time shifts make it necessary to use a PARAFAC2 
      decomposition to solve these two usual problems in the chromatographic 
      determinations. The "second-order advantage" of the PARAFAC2 decomposition allows 
      unequivocal identification according to document SANCO/12495/2011 (taking into 
      account the tolerances for relative retention time and the relative abundance for 
      the diagnostic ions), avoiding false negatives even in the presence of unknown 
      co-eluents. The detection limits (CCalpha) found, from 0.51 to 1.05mugkg(-1), are far 
      below the maximum residue levels (MRLs) established by the European Union for 
      simazine, atrazine, terbuthylazine, ametryn, simetryn, prometryn and terbutryn in 
      oranges. No MRL violations were found in the commercial oranges analyzed.
CI  - Copyright (c) 2013 Elsevier B.V. All rights reserved.
FAU - Herrero, A
AU  - Herrero A
AD  - Department of Chemistry, University of Burgos, Faculty of Sciences, Pza. Misael 
      Banuelos s/n, 09001 Burgos, Spain.
FAU - Ortiz, M C
AU  - Ortiz MC
FAU - Sarabia, L A
AU  - Sarabia LA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130306
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Pesticide Residues)
RN  - 0 (Triazines)
SB  - IM
MH  - Citrus sinensis/*chemistry
MH  - Factor Analysis, Statistical
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Limit of Detection
MH  - Pesticide Residues/*analysis
MH  - Regression Analysis
MH  - Reproducibility of Results
MH  - Solid Phase Extraction/*methods
MH  - Triazines/*analysis
EDAT- 2013/03/26 06:00
MHDA- 2013/07/17 06:00
CRDT- 2013/03/26 06:00
PHST- 2013/01/14 00:00 [received]
PHST- 2013/02/26 00:00 [revised]
PHST- 2013/02/28 00:00 [accepted]
PHST- 2013/03/26 06:00 [entrez]
PHST- 2013/03/26 06:00 [pubmed]
PHST- 2013/07/17 06:00 [medline]
AID - S0021-9673(13)00406-8 [pii]
AID - 10.1016/j.chroma.2013.02.088 [doi]
PST - ppublish
SO  - J Chromatogr A. 2013 May 3;1288:111-26. doi: 10.1016/j.chroma.2013.02.088. Epub 
      2013 Mar 6.