PMID- 23523814
OWN - NLM
STAT- MEDLINE
DCOM- 20131025
LR  - 20130415
IS  - 1525-5069 (Electronic)
IS  - 1525-5050 (Linking)
VI  - 27
IP  - 2
DP  - 2013 May
TI  - Are psychiatric disorders exclusion criteria for video-EEG monitoring and 
      epilepsy surgery in patients with mesial temporal sclerosis?
PG  - 310-4
LID - S1525-5050(13)00064-4 [pii]
LID - 10.1016/j.yebeh.2013.02.014 [doi]
AB  - Epilepsy surgery (ES) is a treatment option for patients with refractory temporal 
      lobe epilepsy (TLE). However, psychiatric disorders (PDs) have been a 
      contraindication for presurgical evaluation in many epilepsy centers. The aim of 
      this study was to evaluate the safety of video-EEG (VEEG) and surgical outcome in 
      patients with refractory TLE and mesial temporal sclerosis (TLE-MTS) associated 
      with PDs. We retrospectively analyzed the clinical, sociodemographic, and VEEG 
      data and surgery outcome of patients with refractory TLE-MTS who underwent ES 
      over the period of 2002 to 2011 and compared data between those with and without 
      PDs. Psychiatric evaluation was performed through DSM-IV and ILAE criteria. 
      Safety during presurgical evaluation was analyzed by the rate of adverse events 
      (AEs). Patients' quality of life (QOL) was measured through ESI-55 and the 
      surgical outcome through Engel's classification. Data from 145 patients were 
      included. The mean VEEG length (93h) was not affected by PDs. Among patients with 
      PDs, 4.91% (3/61) had AEs, and 13.11% (8/61) had psychogenic nonepileptic 
      seizures (PNESs). Among patients without PDs, 4.76% (4/84) had AEs, and 5.95% 
      (5/84) had PNESs. In the first two follow-up years, of the 94 patients who 
      underwent ES, 65.85% (27/41) with PDs and 67.92% (36/53) without PDs became free 
      of disabling seizures (Engel I). No significant differences were observed in the 
      patients' QOL between both groups after surgery. The rate of AEs and seizure 
      outcome did not differ significantly between both groups, reinforcing the idea 
      that PDs should not be absolute exclusion criteria for VEEG monitoring and 
      epilepsy surgery among patients with TLE-MTS.
CI  - Copyright (c) 2013 Elsevier Inc. All rights reserved.
FAU - da Conceicao, Priscila Oliveira
AU  - da Conceicao PO
AD  - Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo 
      (UNIFESP), Sao Paulo, Brazil.
FAU - Nascimento, Pedro Paulo
AU  - Nascimento PP
FAU - Mazetto, Lenon
AU  - Mazetto L
FAU - Alonso, Neide Barreira
AU  - Alonso NB
FAU - Yacubian, Elza Marcia Targas
AU  - Yacubian EM
FAU - de Araujo Filho, Gerardo Maria
AU  - de Araujo Filho GM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130321
PL  - United States
TA  - Epilepsy Behav
JT  - Epilepsy & behavior : E&B
JID - 100892858
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Anterior Temporal Lobectomy/*adverse effects
MH  - *Electroencephalography
MH  - Epilepsy, Temporal Lobe/complications/psychology/*surgery
MH  - Female
MH  - Humans
MH  - Male
MH  - Mental Disorders/complications/diagnosis/*surgery
MH  - Middle Aged
MH  - Psychiatric Status Rating Scales
MH  - Quality of Life
MH  - Retrospective Studies
MH  - Sclerosis/surgery
MH  - Severity of Illness Index
MH  - *Treatment Outcome
MH  - *Video Recording
MH  - Young Adult
EDAT- 2013/03/26 06:00
MHDA- 2013/10/26 06:00
CRDT- 2013/03/26 06:00
PHST- 2012/11/27 00:00 [received]
PHST- 2013/01/07 00:00 [revised]
PHST- 2013/02/16 00:00 [accepted]
PHST- 2013/03/26 06:00 [entrez]
PHST- 2013/03/26 06:00 [pubmed]
PHST- 2013/10/26 06:00 [medline]
AID - S1525-5050(13)00064-4 [pii]
AID - 10.1016/j.yebeh.2013.02.014 [doi]
PST - ppublish
SO  - Epilepsy Behav. 2013 May;27(2):310-4. doi: 10.1016/j.yebeh.2013.02.014. Epub 2013 
      Mar 21.