PMID- 23535332
OWN - NLM
STAT- MEDLINE
DCOM- 20150707
LR  - 20220330
IS  - 1422-0067 (Print)
IS  - 1422-0067 (Electronic)
IS  - 1422-0067 (Linking)
VI  - 14
IP  - 4
DP  - 2013 Mar 27
TI  - Beneficial effects of the RESMENA dietary pattern on oxidative stress in patients 
      suffering from metabolic syndrome with hyperglycemia are associated to dietary 
      TAC and fruit consumption.
PG  - 6903-19
LID - 10.3390/ijms14046903 [doi]
AB  - Hyperglycemia and oxidative stress are conditions directly related to the 
      metabolic syndrome (MetS), whose prevalence is increasing worldwide. This study 
      aimed to evaluate the effectiveness of a new weight-loss dietary pattern on 
      improving the oxidative stress status on patients suffering MetS with 
      hyperglycemia. Seventy-nine volunteers were randomly assigned to two low-calorie 
      diets (-30% Energy): the control diet based on the American Health Association 
      criteria and the RESMENA diet based on a different macronutrient distribution 
      (30% proteins, 30% lipids, 40% carbohydrates), which was characterized by an 
      increase of the meal frequency (seven-times/day), low glycemic load, high 
      antioxidant capacity (TAC) and high n-3 fatty acids content. Dietary records, 
      anthropometrical measurements, biochemical parameters and oxidative stress 
      biomarkers were analyzed before and after the six-month-long study. The RESMENA 
      (Metabolic Syndrome Reduction in Navarra) diet specifically reduced the android 
      fat mass and demonstrated more effectiveness on improving general oxidative 
      stress through a greater decrease of oxidized LDL (oxLDL) values and protection 
      against arylesterase depletion. Interestingly, oxLDL values were associated with 
      dietary TAC and fruit consumption and with changes on body mass index (BMI), 
      waist circumference, fat mass and triacilglyceride (TG) levels. In conclusion, 
      the antioxidant properties of the RESMENA diet provide further benefits to those 
      attributable to weight loss on patients suffering Mets with hyperglycemia.
FAU - de la Iglesia, Rocio
AU  - de la Iglesia R
AD  - Department of Nutrition, Food Sciences and Physiology, University of Navarra, 
      Pamplona 31008, Spain. jalfmtz@unav.es.
FAU - Lopez-Legarrea, Patricia
AU  - Lopez-Legarrea P
FAU - Celada, Paloma
AU  - Celada P
FAU - Sanchez-Muniz, Francisco J
AU  - Sanchez-Muniz FJ
FAU - Martinez, J Alfredo
AU  - Martinez JA
FAU - Zulet, M Angeles
AU  - Zulet MA
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20130327
PL  - Switzerland
TA  - Int J Mol Sci
JT  - International journal of molecular sciences
JID - 101092791
RN  - 0 (Antioxidants)
RN  - 0 (Biomarkers)
RN  - 0 (Lipoproteins, LDL)
RN  - 0 (oxidized low density lipoprotein)
SB  - IM
MH  - Adiposity
MH  - Adult
MH  - Anthropometry
MH  - Antioxidants/*metabolism
MH  - Biomarkers/metabolism
MH  - Blood Pressure
MH  - Body Composition
MH  - *Diet
MH  - Feeding Behavior
MH  - *Fruit
MH  - Humans
MH  - Hyperglycemia/complications/*diet therapy/pathology/physiopathology
MH  - Lipoproteins, LDL/metabolism
MH  - Metabolic Syndrome/complications/*diet therapy/*pathology/physiopathology
MH  - *Oxidative Stress
PMC - PMC3645670
EDAT- 2013/03/29 06:00
MHDA- 2013/03/29 06:01
PMCR- 2013/04/01
CRDT- 2013/03/29 06:00
PHST- 2013/01/30 00:00 [received]
PHST- 2013/03/08 00:00 [revised]
PHST- 2013/03/19 00:00 [accepted]
PHST- 2013/03/29 06:00 [entrez]
PHST- 2013/03/29 06:00 [pubmed]
PHST- 2013/03/29 06:01 [medline]
PHST- 2013/04/01 00:00 [pmc-release]
AID - ijms14046903 [pii]
AID - ijms-14-06903 [pii]
AID - 10.3390/ijms14046903 [doi]
PST - epublish
SO  - Int J Mol Sci. 2013 Mar 27;14(4):6903-19. doi: 10.3390/ijms14046903.