PMID- 23541535
OWN - NLM
STAT- MEDLINE
DCOM- 20131030
LR  - 20130415
IS  - 1773-0597 (Electronic)
IS  - 0181-5512 (Linking)
VI  - 36
IP  - 4
DP  - 2013 Apr
TI  - [Analysis of macular ganglion cell complex (GCC) with spectral-domain optical 
      coherence tomography (SD-OCT) in glaucoma].
PG  - 299-309
LID - S0181-5512(13)00058-2 [pii]
LID - 10.1016/j.jfo.2013.01.005 [doi]
AB  - Early detection of ganglion cell loss is possible with new algorithms for the 
      assessment of the Macular Ganglion Cell Complex (GCC) by SD-OCT. The various data 
      acquisition protocols used by the various versions of software, as well as their 
      accuracy and reproducibility, must be taken into account. Current results show 
      similar ability to detect glaucoma as compared to Retinal Nerve Fiber Layer 
      thickness (RNFL), with some limitations, possible artifacts, and interpretation 
      pitfalls which must be taken into account. The role of the significance map and 
      of various indices (Focal Loss Volume, Global Loss Volume, GCIPL minimum...); 
      data obtained in the setting of various clinical entities (tilted disc, 
      peripapillary atrophy, large and small optic discs, high myopia...); and 
      detection of progression, especially in advanced glaucoma, underline the role of 
      macular GCC analysis as a complementary method to peripapillary RNFL thickness. 
      The diagnostic precision and better reproducibility of these new software 
      protocols offer new perspectives in the detection and management of progression 
      in various stages of the management of glaucomatous optic neuropathy.
CI  - Copyright (c) 2013 Elsevier Masson SAS. All rights reserved.
FAU - Renard, J-P
AU  - Renard JP
AD  - Service d'ophtalmologie, hopital du Val-de-Grace, 74, boulevard de Port royal, 
      75005 Paris, France. pr_renard@yahoo.fr
FAU - Fenolland, J-R
AU  - Fenolland JR
FAU - El Chehab, H
AU  - El Chehab H
FAU - Francoz, M
AU  - Francoz M
FAU - Marill, A-M
AU  - Marill AM
FAU - Messaoudi, R
AU  - Messaoudi R
FAU - Delbarre, M
AU  - Delbarre M
FAU - Marechal, M
AU  - Marechal M
FAU - Michel, S
AU  - Michel S
FAU - Giraud, J-M
AU  - Giraud JM
LA  - fre
PT  - English Abstract
PT  - Journal Article
PT  - Review
TT  - Analyse du complexe cellulaire ganglionnaire maculaire (GCC) en tomographie par 
      coherence optique (SD-OCT) dans le glaucome.
DEP - 20130329
PL  - France
TA  - J Fr Ophtalmol
JT  - Journal francais d'ophtalmologie
JID - 7804128
SB  - IM
MH  - Disease Progression
MH  - Fluorescein Angiography
MH  - Glaucoma/complications/*pathology
MH  - Humans
MH  - Macula Lutea/*pathology
MH  - Myopia/complications/pathology
MH  - Retinal Ganglion Cells/*pathology
MH  - Sensitivity and Specificity
MH  - *Tomography, Optical Coherence/methods
EDAT- 2013/04/02 06:00
MHDA- 2013/10/31 06:00
CRDT- 2013/04/02 06:00
PHST- 2013/01/14 00:00 [received]
PHST- 2013/01/29 00:00 [accepted]
PHST- 2013/04/02 06:00 [entrez]
PHST- 2013/04/02 06:00 [pubmed]
PHST- 2013/10/31 06:00 [medline]
AID - S0181-5512(13)00058-2 [pii]
AID - 10.1016/j.jfo.2013.01.005 [doi]
PST - ppublish
SO  - J Fr Ophtalmol. 2013 Apr;36(4):299-309. doi: 10.1016/j.jfo.2013.01.005. Epub 2013 
      Mar 29.