PMID- 2354491 OWN - NLM STAT- MEDLINE DCOM- 19900725 LR - 20061115 IS - 0008-7335 (Print) IS - 0008-7335 (Linking) VI - 129 IP - 20 DP - 1990 May 18 TI - [Antibodies against deoxyribonucleoproteins in circulating immune complexes in the blood of patients with autoimmune diseases]. PG - 622-4 AB - In 40 patients with various autoimmune diseases antibodies against desoxyribonucleoprotein (DNP) were assessed by enzyme immunoanalysis (ELISA) in serum and after dissociation of the isolated precipitate of circulating immune complexes (CIC) in the presence of polyethylene glycol. The results indicate that antibodies against DNP are not specific for systemic lupus erythematosus (SLE) and can be detected in serum and in particular in CIC in various autoimmune conditions. In SLE they may be important for evaluation of the activity of the disease, in particular if estimated concurrently in serum and in CIC. FAU - Matl, I AU - Matl I AD - Katedra interniho lekarstvi, Institutu pro dalsi vzdelavani lekaru a farmaceutu, Praha. FAU - Haskova, V AU - Haskova V FAU - Dostal, C AU - Dostal C FAU - Kaslik, J AU - Kaslik J LA - cze PT - English Abstract PT - Journal Article TT - Protilatky proti deoxyribonukleoproteinu v cirkulujicich imunitnich komplexech a serech nemocnych s nekterymi autoimunitnimi chorobami. PL - Czech Republic TA - Cas Lek Cesk JT - Casopis lekaru ceskych JID - 0004743 RN - 0 (Antigen-Antibody Complex) RN - 0 (Autoantibodies) RN - 0 (Deoxyribonucleoproteins) SB - IM MH - Antigen-Antibody Complex/*immunology MH - Autoantibodies/*analysis MH - Autoimmune Diseases/*immunology MH - Deoxyribonucleoproteins/*immunology MH - Enzyme-Linked Immunosorbent Assay MH - Humans MH - Lupus Erythematosus, Systemic/immunology EDAT- 1990/05/18 00:00 MHDA- 1990/05/18 00:01 CRDT- 1990/05/18 00:00 PHST- 1990/05/18 00:00 [pubmed] PHST- 1990/05/18 00:01 [medline] PHST- 1990/05/18 00:00 [entrez] PST - ppublish SO - Cas Lek Cesk. 1990 May 18;129(20):622-4.