PMID- 23545832
OWN - NLM
STAT- MEDLINE
DCOM- 20140905
LR  - 20130402
IS  - 1672-7347 (Print)
IS  - 1672-7347 (Linking)
VI  - 38
IP  - 3
DP  - 2013 Mar
TI  - [Visfatin level after laparoscopic Roux-en-Y gastric bypass surgery in patients 
      with Type 2 diabetes].
PG  - 258-61
LID - 10.3969/j.issn.1672-7347.2013.03.007 [doi]
AB  - OBJECTIVE: To investigate the change in serum visfatin level after laparoscopic 
      Roux-en-Y gastric bypass surgery in patients with Type 2 diabetes mellitus (T2DM) 
      and to explore the relationship between visfatin insulin resistance and diabetes. 
      METHODS: Thirty-three patients with Type 2 diabetes were studied before and after 
      the gastric bypass surgery. The level of fasting serum visfatin was measured by 
      enzyme-linked immunosorbent assay. Fasting plasma glucose (FPG), glycated 
      hemoglobin (HbA1c) and fasting insulin (FINS) were measured before and after the 
      gastric bypass surgery. RESULTS: Compared with before the operation, the 
      indicators of HbA1c, FINS, and insulin resistance index (HOMA-IR) were decreased 
      after the laparoscopic Roux-en-Y gastric bypass surgery. The body mass index 
      (BMI) [(24.53 +/- 0.62) kg/m(2) vs (26.71 +/- 0.69) kg/m2] was decreased, with 
      significant difference (P<0.001). The serum visfatin level [(9.79 +/- 0.64) ng/mL] 
      was significantly lower than before the operation [(38.24 +/- 5.32) ng/mL], with 
      significant difference (P<0.001). CONCLUSION: Serum level of visfatin is 
      decreased in T2DM patients who undergo gastric bypass surgry, reflecting an 
      improvement in insulin resistance and diabetes.
FAU - Liu, Yiqun
AU  - Liu Y
AD  - Department of Endocrinology, Third Xiangya Hospital, Central South University, 
      Changsha 410013, China. easd04mzh@126.com
FAU - Xiong, Jing
AU  - Xiong J
FAU - He, Honghui
AU  - He H
FAU - Zhu, Shaihong
AU  - Zhu S
FAU - Mo, Zhaohui
AU  - Mo Z
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Zhong Nan Da Xue Xue Bao Yi Xue Ban
JT  - Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. 
      Medical sciences
JID - 101230586
RN  - EC 2.4.2.12 (Nicotinamide Phosphoribosyltransferase)
SB  - IM
MH  - Diabetes Mellitus, Type 2/blood/*surgery
MH  - Female
MH  - *Gastric Bypass
MH  - Humans
MH  - Insulin Resistance
MH  - *Laparoscopy
MH  - Male
MH  - Middle Aged
MH  - Nicotinamide Phosphoribosyltransferase/*blood
MH  - Postoperative Period
EDAT- 2013/04/03 06:00
MHDA- 2014/09/06 06:00
CRDT- 2013/04/03 06:00
PHST- 2013/04/03 06:00 [entrez]
PHST- 2013/04/03 06:00 [pubmed]
PHST- 2014/09/06 06:00 [medline]
AID - 10.3969/j.issn.1672-7347.2013.03.007 [doi]
PST - ppublish
SO  - Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2013 Mar;38(3):258-61. doi: 
      10.3969/j.issn.1672-7347.2013.03.007.