PMID- 23548392 OWN - NLM STAT- MEDLINE DCOM- 20130805 LR - 20170310 IS - 0022-9040 (Print) IS - 0022-9040 (Linking) VI - 53 IP - 2 DP - 2013 TI - [Mitral regurgitation and coronary stenosis in postmyocardial infarction patients]. PG - 55-60 AB - The results of investigations devoted to relationship of mitral regurgitation (MR) and scars are contradictive, data on relationship of MR and localization of coronary lesions are few. Purpose. To determinate relationship of moderate or severe MR to localization of coronary stenosis in postmyocardial infarction patients. Methods. There were 1167 patients with no MR and 403 patients with moderate or severe MR. Results. Patients with MR had more severe New York Heart Association (NYHA) functional class (III-IV) (35.5 vs. 11.2%). Echocardiographic indices of left atrial dimension (23.5+/-2.9 vs. 20.3+/-2.1 mm/m) and extent of left ventricular (LV) wall motion abnormalities (32.8+/-14.9 vs. 23.6+/-12.7%) were higher in patients with MR as well as reduced LV systolic function (LV ejection fraction <50% - 63.7 vs. 25.6%) and LV dilatation (63.3 vs. 19.9%, all p<0.001). Rates of multivessel coronary artery involvement (three or more arteries) (27.5 vs. 18.3%, p=0.001), lesions in left main coronary artery (7.2 vs. 1.1%), circumflex (36.2 vs. 26.7), and right coronary artery (57.3 vs. 44.9%) were higher in patients with MR (all p<0.001). According to results of multivariate analysis MR was independently associated with LV dilatation, NYHA class of congestive heart failure, index of left atrial size, and extent of LV wall motion abnormalities. Moderate or severe chronic MR was not related to localization of coronary stenosis in these patients. FAU - Iaroslavskaia, E I AU - Iaroslavskaia EI FAU - Kuznetsov, V A AU - Kuznetsov VA FAU - Pushkarev, G S AU - Pushkarev GS FAU - Krinochkin, D V AU - Krinochkin DV FAU - Zyrianov, I P AU - Zyrianov IP FAU - Kolunin, G V AU - Kolunin GV LA - rus PT - English Abstract PT - Journal Article PL - Russia (Federation) TA - Kardiologiia JT - Kardiologiia JID - 0376351 SB - IM MH - Adult MH - *Coronary Angiography/methods/statistics & numerical data MH - *Coronary Stenosis/complications/diagnosis MH - Echocardiography/methods MH - Female MH - *Heart Atria/pathology/physiopathology MH - Heart Failure/etiology/physiopathology MH - Humans MH - Male MH - Middle Aged MH - *Mitral Valve Insufficiency/etiology/physiopathology MH - Multivariate Analysis MH - Myocardial Infarction/*complications/epidemiology MH - Registries MH - Risk Factors MH - Severity of Illness Index MH - Statistics as Topic MH - *Ventricular Function, Left EDAT- 2013/04/04 06:00 MHDA- 2013/08/06 06:00 CRDT- 2013/04/04 06:00 PHST- 2013/04/04 06:00 [entrez] PHST- 2013/04/04 06:00 [pubmed] PHST- 2013/08/06 06:00 [medline] PST - ppublish SO - Kardiologiia. 2013;53(2):55-60.