PMID- 23551214
OWN - NLM
STAT- MEDLINE
DCOM- 20131118
LR  - 20221207
IS  - 1365-2230 (Electronic)
IS  - 0307-6938 (Linking)
VI  - 38
IP  - 4
DP  - 2013 Jun
TI  - Combination of intense pulsed light and fractional CO(2) laser treatments for 
      patients with acne with inflammatory and scarring lesions.
PG  - 344-51
LID - 10.1111/ced.12010 [doi]
AB  - BACKGROUND: Various laser and light sources are been used increasingly in 
      cosmetic dermatology. AIM: To evaluate the efficacy and safety of combination 
      intense pulsed light (IPL) and fractional CO2 laser in treating patients with 
      acne with both inflammatory and scarring lesions. METHODS: In total, 37 Chinese 
      patients with acne with facial inflammatory and scar lesions were treated. 
      Successive sessions of 4-6 IPL treatments followed by 2 sessions of fractional 
      CO2 laser treatments were applied. Effectiveness was determined by the 
      dermatologist's evaluation, patient self-assessment, and devices that measure 
      skin colour, sebum secretion and skin hydration. RESULTS: IPL treatments 
      significantly reduced the inflammatory lesion score and the atrophic scar score 
      compared with baseline. Subsequent fractional CO2 laser treatments further 
      decreased the atrophic scar score. Both scores remained low when patients were 
      followed up at 6 months. Around 90% of the patients experienced significant or 
      moderate overall improvement, and almost 80% patients rated their results as 
      'excellent' or 'good'. The melanin index (MI), erythema index (EI) and skin sebum 
      level all significantly decreased after IPL treatments, and the EI and sebum 
      level were still low when assessed at the 3-month follow-up, although the MI had 
      increased again. The adverse effects (AEs) of both treatments were transient and 
      bearable. CONCLUSIONS: IPL in combination with fractional CO2 laser was effective 
      in treating patients with acne with both inflammatory lesions and atrophic scars, 
      and the AEs were acceptable.
CI  - (c) The Author(s) CED (c) 2013 British Association of Dermatologists.
FAU - Wang, B
AU  - Wang B
AD  - Department of Dermatology, No. 1 Hospital of China Medical University, Shenyang, 
      China Sheftel Associates Dermatology, Tucson, AZ, USA.
FAU - Wu, Y
AU  - Wu Y
FAU - Luo, Y-J
AU  - Luo YJ
FAU - Xu, X-G
AU  - Xu XG
FAU - Xu, T-H
AU  - Xu TH
FAU - Chen, J Z S
AU  - Chen JZ
FAU - Gao, X-H
AU  - Gao XH
FAU - Chen, H-D
AU  - Chen HD
FAU - Li, Y-H
AU  - Li YH
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130403
PL  - England
TA  - Clin Exp Dermatol
JT  - Clinical and experimental dermatology
JID - 7606847
SB  - IM
MH  - Acne Vulgaris/complications/*therapy
MH  - Adult
MH  - Asian People
MH  - China
MH  - Cicatrix/etiology/*therapy
MH  - Female
MH  - Humans
MH  - Inflammation/etiology/*therapy
MH  - *Intense Pulsed Light Therapy
MH  - Lasers, Gas/*therapeutic use
MH  - Low-Level Light Therapy
MH  - Male
MH  - Patient Satisfaction
MH  - Young Adult
EDAT- 2013/04/05 06:00
MHDA- 2013/11/19 06:00
CRDT- 2013/04/05 06:00
PHST- 2013/04/05 06:00 [entrez]
PHST- 2013/04/05 06:00 [pubmed]
PHST- 2013/11/19 06:00 [medline]
AID - 10.1111/ced.12010 [doi]
PST - ppublish
SO  - Clin Exp Dermatol. 2013 Jun;38(4):344-51. doi: 10.1111/ced.12010. Epub 2013 Apr 
      3.