PMID- 23553462
OWN - NLM
STAT- MEDLINE
DCOM- 20131030
LR  - 20161125
IS  - 1098-2337 (Electronic)
IS  - 0096-140X (Linking)
VI  - 39
IP  - 4
DP  - 2013 Jul-Aug
TI  - Effects of oxytocin on women's aggression depend on state anxiety.
PG  - 316-22
LID - 10.1002/ab.21478 [doi]
AB  - Research on oxytocin (OT) indicates that it has stress reducing effects. This 
      leads to opposing predictions of decreased and increased aggression which we 
      examine in this study. Following completion of a state anxiety measure and 
      administration of OT or a placebo, female participants took part in a competitive 
      aggression game (PSAP) for a monetary prize which, if won, would be paid to a 
      loved one. In the game, three options were available: participants could earn 
      points; attack their opponent by deducting points; and defend themselves against 
      point deduction by their opponent. There was no main effect of OT on these 
      responses, however there was an interaction with state anxiety. In the placebo 
      condition, women higher in state anxiety showed a significantly higher ratio of 
      Attack-to-Earn responses than low anxiety women. Under oxytocin, there was a 
      significant reduction in their Attack:Earn ratio resulting in no significant 
      difference between high and low state anxiety groups. There was a similar trend 
      for the Defend:Earn ratio. The reduction of reactive aggression in state anxious 
      women supports the view that OT may decrease negative behavior and increase 
      constructive behavior even under conditions of provocation.
CI  - (c) 2013 Wiley Periodicals, Inc.
FAU - Campbell, Anne
AU  - Campbell A
AD  - Psychology Department, Durham University, Durham, United Kingdom. 
      a.c.campbell@durham.ac.uk
FAU - Hausmann, Markus
AU  - Hausmann M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130403
PL  - United States
TA  - Aggress Behav
JT  - Aggressive behavior
JID - 7502265
RN  - 50-56-6 (Oxytocin)
SB  - IM
MH  - Adult
MH  - Anxiety/*psychology
MH  - Competitive Behavior/*physiology
MH  - Female
MH  - Humans
MH  - Impulsive Behavior/*psychology
MH  - Interpersonal Relations
MH  - Motivation
MH  - Oxytocin/*physiology
MH  - Photic Stimulation/methods
MH  - Play and Playthings/*psychology
MH  - Social Behavior
MH  - United Kingdom
MH  - Young Adult
EDAT- 2013/04/05 06:00
MHDA- 2013/10/31 06:00
CRDT- 2013/04/05 06:00
PHST- 2012/08/15 00:00 [received]
PHST- 2013/01/17 00:00 [accepted]
PHST- 2013/04/05 06:00 [entrez]
PHST- 2013/04/05 06:00 [pubmed]
PHST- 2013/10/31 06:00 [medline]
AID - 10.1002/ab.21478 [doi]
PST - ppublish
SO  - Aggress Behav. 2013 Jul-Aug;39(4):316-22. doi: 10.1002/ab.21478. Epub 2013 Apr 3.