PMID- 23559486
OWN - NLM
STAT- MEDLINE
DCOM- 20140724
LR  - 20131205
IS  - 1522-2586 (Electronic)
IS  - 1053-1807 (Linking)
VI  - 38
IP  - 6
DP  - 2013 Dec
TI  - Noncontrast-enhanced magnetic resonance angiography and venography imaging with 
      enhanced angiography.
PG  - 1539-48
LID - 10.1002/jmri.24128 [doi]
AB  - PURPOSE: To achieve simultaneous high-resolution magnetic resonance angiography 
      and venography (MRAV) imaging in terms of enhanced time-of-flight (TOF) 
      angiography and susceptibility-weighted imaging (SWI), with a clear separation of 
      arteries and veins. MATERIALS AND METHODS: A new flow rephase/dephase interleaved 
      double-echo sequence was introduced that facilitates multiple types of imaging 
      contrast, i.e., TOF, SWI, and dark blood, in a single acquisition. A nonlinear 
      subtraction (NLS) method is proposed and assessed to maximally enhance 
      angiography contrast with minimum venous contamination. RESULTS: Fully flow 
      rephased TOF MRA and SWI MRV data were acquired simultaneously, along with an 
      extra flow dephased dark blood image for angiography enhancement calculation. 
      Compared to linear subtraction methods, the proposed NLS method was able to 
      enhance angiography contrast while effectively eliminating vein-tissue contrast. 
      The NLS method even outperformed low-dose contrast-enhanced MRA for a clean, 
      enhanced angiography map. CONCLUSION: Using the proposed interleaved double-echo 
      sequence along with the NLS postprocessing method, one can simultaneously obtain 
      both high-quality SWI and significantly enhanced TOF MRA with clear separation of 
      arterial and venous maps.
CI  - Copyright (c) 2013 Wiley Periodicals, Inc.
FAU - Ye, Yongquan
AU  - Ye Y
AD  - Department of Radiology, Wayne State University, Detroit, Michigan, USA.
FAU - Hu, Jiani
AU  - Hu J
FAU - Wu, Dongmei
AU  - Wu D
FAU - Haacke, E Mark
AU  - Haacke EM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20130404
PL  - United States
TA  - J Magn Reson Imaging
JT  - Journal of magnetic resonance imaging : JMRI
JID - 9105850
SB  - IM
MH  - Adult
MH  - Arteries/*anatomy & histology
MH  - Female
MH  - Humans
MH  - Image Enhancement/methods
MH  - Image Interpretation, Computer-Assisted/*methods
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Multimodal Imaging/*methods
MH  - Phlebography/*methods
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - *Subtraction Technique
MH  - Veins/*anatomy & histology
OTO - NOTNLM
OT  - MRAV
OT  - SWI
OT  - TOF MRA
OT  - nonlinear processing
EDAT- 2013/04/06 06:00
MHDA- 2014/07/25 06:00
CRDT- 2013/04/06 06:00
PHST- 2012/04/20 00:00 [received]
PHST- 2013/02/20 00:00 [accepted]
PHST- 2013/04/06 06:00 [entrez]
PHST- 2013/04/06 06:00 [pubmed]
PHST- 2014/07/25 06:00 [medline]
AID - 10.1002/jmri.24128 [doi]
PST - ppublish
SO  - J Magn Reson Imaging. 2013 Dec;38(6):1539-48. doi: 10.1002/jmri.24128. Epub 2013 
      Apr 4.