PMID- 23560876
OWN - NLM
STAT- MEDLINE
DCOM- 20140630
LR  - 20231213
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 61
IP  - 16
DP  - 2013 Apr 24
TI  - Simultaneous determination of banned acid orange dyes and basic orange dyes in 
      foodstuffs by liquid chromatography-tandem electrospray ionization mass 
      spectrometry via negative/positive ion switching mode.
PG  - 3834-41
LID - 10.1021/jf400619y [doi]
AB  - Simultaneous detection of two classes of dyes possessing different chemical 
      properties is difficult. In this study, through negative/positive ion switching 
      mode, simultaneous determination of four typical acid orange dyes and three 
      typical basic orange dyes was achieved by a single high-performance liquid 
      chromatography-tandem mass spectrometry (LC-MS/MS) method, and the analytical 
      efficiency of multiresidues identification was greatly improved. To enhance 
      detection sensitivity, the sample pretreatment conditions and HPLC-MS/MS 
      determining conditions were carefully optimized. Under optimal conditions, good 
      linearity was obtained over the range of 5-500 mug L(-1) with a correlation 
      coefficient (R(2)) >0.9998. Limits of detection (LODs) and limits of 
      quantification (LOQs) of the seven dyes were 0.5-3.0 and 2.0-6.0 mug kg(-1), 
      respectively. The recoveries of the seven dyes in soybean products and marinated 
      eggs were 74-126% with relative standard deviations (RSDs) of 2.22-25.4%, 
      suggesting the developed method is promising for the accurate quantification of 
      the seven dyes at trace levels in foods.
FAU - Fang, Guozhen
AU  - Fang G
AD  - Key Laboratory of Food Nutrition and Safety, Ministry of Education, Tianjin Key 
      Laboratory of Food Nutrition and Safety, Tianjin University of Science and 
      Technology , Tianjin 300457, China.
FAU - Wu, Yu
AU  - Wu Y
FAU - Dong, Xiaomeng
AU  - Dong X
FAU - Liu, Cuicui
AU  - Liu C
FAU - He, Shaoyuan
AU  - He S
FAU - Wang, Shuo
AU  - Wang S
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130416
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Azo Compounds)
RN  - 0 (Coloring Agents)
SB  - IM
MH  - Azo Compounds/*analysis
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Coloring Agents/*analysis
MH  - Eggs/analysis
MH  - Food Analysis/*methods
MH  - Food Contamination/*analysis/legislation & jurisprudence
MH  - Mass Spectrometry/*methods
MH  - Glycine max/chemistry
MH  - Spectrometry, Mass, Electrospray Ionization/methods
MH  - Tandem Mass Spectrometry/methods
EDAT- 2013/04/09 06:00
MHDA- 2014/07/01 06:00
CRDT- 2013/04/09 06:00
PHST- 2013/04/09 06:00 [entrez]
PHST- 2013/04/09 06:00 [pubmed]
PHST- 2014/07/01 06:00 [medline]
AID - 10.1021/jf400619y [doi]
PST - ppublish
SO  - J Agric Food Chem. 2013 Apr 24;61(16):3834-41. doi: 10.1021/jf400619y. Epub 2013 
      Apr 16.