PMID- 23562332
OWN - NLM
STAT- MEDLINE
DCOM- 20140320
LR  - 20130802
IS  - 1878-1632 (Electronic)
IS  - 1529-9430 (Linking)
VI  - 13
IP  - 8
DP  - 2013 Aug
TI  - Tanycytic ependymoma of the filum terminale associated with multiple endocrine 
      neoplasia type 1: first reported case.
PG  - e49-54
LID - S1529-9430(13)00266-0 [pii]
LID - 10.1016/j.spinee.2013.02.066 [doi]
AB  - BACKGROUND CONTEXT: Ependymoma associated with multiple endocrine neoplasia type 
      1 (MEN-1) is an extremely rare clinical entity. To the best of our knowledge, 
      only five cases of ependymoma associated with MEN-1 have been previously 
      described. Furthermore, there has been no case of tanycytic ependymoma of the 
      filum terminale associated with MEN-1. PURPOSE: The present case report 
      illustrates a 53-year-old man with tanycytic ependymoma of the filum terminale 
      associated with MEN-1. We review the literature on ependymoma with MEN-1 and 
      tanycytic ependymoma of the cauda equina region and also discuss the risk of 
      recurrence. STUDY DESIGN: A case report. METHODS: The patient presented with 
      complaints of nocturnal pain in the lower back, accompanied by numbness around 
      the anus and intermittent claudication for approximately 1 year. Magnetic 
      resonance imaging (MRI) identified an intradural-enhancing, large mass lesion at 
      the level from Th12 to L2 vertebrae, with a cranial cystic lesion. RESULTS: 
      Open-door laminoplasty of the Th12, L1, and L2 and en bloc tumor resection with 
      thickened filum terminale were performed. Histopathologic examination of the 
      tumor specimens showed tanycytic ependymoma (World Health Organization 
      Classification Grade II). At the time of the 2-year and 8-month follow-up 
      examination, MRI did not show tumor recurrence. CONCLUSIONS: This is the first 
      reported case of this clinical entity. A careful follow-up of patients with this 
      unusual tumor is strongly recommended.
CI  - Copyright (c) 2013 Elsevier Inc. All rights reserved.
FAU - Funayama, Toru
AU  - Funayama T
AD  - Department of Orthopaedic Surgery, Graduate School of Comprehensive Human 
      Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, 
      Japan. funatoru3@gmail.com
FAU - Sakane, Masataka
AU  - Sakane M
FAU - Yoshizawa, Tomohiro
AU  - Yoshizawa T
FAU - Takeuchi, Yousuke
AU  - Takeuchi Y
FAU - Ochiai, Naoyuki
AU  - Ochiai N
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20130403
PL  - United States
TA  - Spine J
JT  - The spine journal : official journal of the North American Spine Society
JID - 101130732
SB  - IM
MH  - Cauda Equina/*pathology/surgery
MH  - Ependymoma/*complications/pathology/surgery
MH  - Humans
MH  - Laminectomy
MH  - Lumbar Vertebrae/pathology/surgery
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Middle Aged
MH  - Multiple Endocrine Neoplasia Type 1/*complications/pathology/surgery
MH  - Peripheral Nervous System Neoplasms/*complications/pathology/surgery
OTO - NOTNLM
OT  - Conus medullaris
OT  - Filum terminale
OT  - Multiple endocrine neoplasia type 1
OT  - Tanycytic ependymoma
EDAT- 2013/04/09 06:00
MHDA- 2014/03/22 06:00
CRDT- 2013/04/09 06:00
PHST- 2012/03/21 00:00 [received]
PHST- 2013/02/25 00:00 [revised]
PHST- 2013/02/25 00:00 [accepted]
PHST- 2013/04/09 06:00 [entrez]
PHST- 2013/04/09 06:00 [pubmed]
PHST- 2014/03/22 06:00 [medline]
AID - S1529-9430(13)00266-0 [pii]
AID - 10.1016/j.spinee.2013.02.066 [doi]
PST - ppublish
SO  - Spine J. 2013 Aug;13(8):e49-54. doi: 10.1016/j.spinee.2013.02.066. Epub 2013 Apr 
      3.