PMID- 23568912
OWN - NLM
STAT- MEDLINE
DCOM- 20130522
LR  - 20130409
IS  - 1943-3700 (Electronic)
IS  - 0090-3558 (Linking)
VI  - 49
IP  - 2
DP  - 2013 Apr
TI  - Prevalence of neutralizing antibodies to rabies virus in serum of seven species 
      of insectivorous bats from Colorado and New Mexico, United States.
PG  - 367-74
LID - 10.7589/2012-05-124 [doi]
AB  - We determined the presence of rabies-virus-neutralizing antibodies (RVNA) in 
      serum of 721 insectivorous bats of seven species captured, sampled, and released 
      in Colorado and New Mexico, United States in 2003-2005. A subsample of 160 bats 
      was tested for rabies-virus RNA in saliva. We sampled little brown bats (Myotis 
      lucifugus) at two maternity roosts in Larimer County, Colorado; big brown bats 
      (Eptesicus fuscus) at three maternity roosts in Morgan County, Colorado; and big 
      brown bats at five maternity roosts in Larimer County. We also sampled hoary bats 
      (Lasiurus cinereus) and silver-haired bats (Lasionycteris noctivagans) captured 
      while drinking or foraging over water in Bernalillo County, New Mexico and at 
      various locations in Larimer County. Big brown bats, little brown bats, 
      long-legged myotis (Myotis volans), long-eared myotis (Myotis evotis), and 
      fringed myotis (Myotis thysanodes) were also sampled over water in Larimer 
      County. All species except long-eared myotis included individuals with RVNA, with 
      prevalences ranging from 7% in adult female silver-haired bats to 32% in adult 
      female hoary bats. None of the bats had detectable rabies-virus RNA in 
      oropharyngeal swabs, including 51 bats of 5 species that had RVNA in serum. 
      Antibody-positive bats were present in nine of the 10 maternity colonies sampled. 
      These data suggest that wild bats are commonly exposed to rabies virus and 
      develop a humoral immune response suggesting some degree of viral replication, 
      but many infections fail to progress to clinical disease.
FAU - Bowen, Richard A
AU  - Bowen RA
AD  - Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 
      80523, USA. richard.bowen@colostate.edu
FAU - O'Shea, Thomas J
AU  - O'Shea TJ
FAU - Shankar, Vidya
AU  - Shankar V
FAU - Neubaum, Melissa A
AU  - Neubaum MA
FAU - Neubaum, Daniel J
AU  - Neubaum DJ
FAU - Rupprecht, Charles E
AU  - Rupprecht CE
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - United States
TA  - J Wildl Dis
JT  - Journal of wildlife diseases
JID - 0244160
RN  - 0 (Antibodies, Viral)
RN  - 0 (RNA, Viral)
SB  - IM
MH  - Animals
MH  - Antibodies, Viral/*blood
MH  - *Chiroptera/immunology/virology
MH  - Colorado/epidemiology
MH  - Female
MH  - Male
MH  - New Mexico/epidemiology
MH  - RNA, Viral/analysis
MH  - Rabies/epidemiology/*veterinary
MH  - Rabies virus/immunology/isolation & purification
MH  - Saliva/virology
MH  - Seroepidemiologic Studies
MH  - Species Specificity
EDAT- 2013/04/10 06:00
MHDA- 2013/05/23 06:00
CRDT- 2013/04/10 06:00
PHST- 2013/04/10 06:00 [entrez]
PHST- 2013/04/10 06:00 [pubmed]
PHST- 2013/05/23 06:00 [medline]
AID - 49/2/367 [pii]
AID - 10.7589/2012-05-124 [doi]
PST - ppublish
SO  - J Wildl Dis. 2013 Apr;49(2):367-74. doi: 10.7589/2012-05-124.