PMID- 23571461
OWN - NLM
STAT- MEDLINE
DCOM- 20140509
LR  - 20130722
IS  - 1523-6536 (Electronic)
IS  - 1083-8791 (Linking)
VI  - 19
IP  - 8
DP  - 2013 Aug
TI  - Clinical guide to ABO-incompatible allogeneic stem cell transplantation.
PG  - 1152-8
LID - S1083-8791(13)00145-6 [pii]
LID - 10.1016/j.bbmt.2013.03.018 [doi]
AB  - The independent genomic inheritance of the human leukocyte antigen (HLA) and the 
      ABO-blood group system allows for HLA-matched hematopoietic progenitor cell 
      transplantation (HCT) to occur in donors who are not matched for ABO blood 
      groups. In fact, nearly one-half of all HCT will involve recipient-donor ABO 
      incompatibility. This places the recipient at increased risk for acute and 
      delayed hemolytic reactions, delayed RBC engraftment, and pure red blood cell 
      aplasia. Additionally, clinical and laboratory evaluation for potential non-ABO, 
      minor RBC antigen-antibody discrepancies may be beneficial to facilitate safe 
      transfusions before, during, and after transplantation. In addition to posing 
      potential clinical risks, analyses of outcomes in ABO-incompatible HCT have 
      yielded inconsistent results with respect to overall survival, relapse risk, 
      incidence of acute or chronic graft-versus-host disease, and engraftment of 
      platelets and granulocytes. As such, pretransplantation donor-recipient 
      evaluation and management for ABO-incompatible HCT requires adopting unique 
      strategies when major, minor, and bidirectional differences exist. These 
      strategies have the potential to improve patient outcomes and allow for effective 
      management of the blood bank inventory. The purpose of this article is to 
      describe practical approaches to screening for and managing ABO-incompatible HCT, 
      with the goal of reducing preventable morbidity and mortality after 
      transplantation.
CI  - Copyright (c) 2013 American Society for Blood and Marrow Transplantation. All 
      rights reserved.
FAU - Booth, Garrett S
AU  - Booth GS
AD  - Department of Pathology, Microbiology and Immunology, Vanderbilt University 
      Medical Center, Nashville, TN 37232, USA. garrett.s.booth@vanderbilt.edu
FAU - Gehrie, Eric A
AU  - Gehrie EA
FAU - Bolan, Charles D
AU  - Bolan CD
FAU - Savani, Bipin N
AU  - Savani BN
LA  - eng
PT  - Journal Article
DEP - 20130406
PL  - United States
TA  - Biol Blood Marrow Transplant
JT  - Biology of blood and marrow transplantation : journal of the American Society for 
      Blood and Marrow Transplantation
JID - 9600628
RN  - 0 (ABO Blood-Group System)
SB  - IM
CIN - Biol Blood Marrow Transplant. 2013 Dec;19(12):1760. PMID: 24120381
CIN - Biol Blood Marrow Transplant. 2013 Dec;19(12):1760-1. PMID: 24125949
MH  - ABO Blood-Group System/*immunology
MH  - Blood Group Incompatibility/*immunology
MH  - Hematopoietic Stem Cell Transplantation/*methods
MH  - Hemolysis/immunology
MH  - Humans
MH  - Transplantation Conditioning/methods
MH  - Transplantation Immunology
MH  - Transplantation, Homologous/methods
OTO - NOTNLM
OT  - Blood group
OT  - Hemolysis
OT  - Stem cell
OT  - Transfusion
OT  - Transplant
EDAT- 2013/04/11 06:00
MHDA- 2014/05/10 06:00
CRDT- 2013/04/11 06:00
PHST- 2013/02/17 00:00 [received]
PHST- 2013/03/30 00:00 [accepted]
PHST- 2013/04/11 06:00 [entrez]
PHST- 2013/04/11 06:00 [pubmed]
PHST- 2014/05/10 06:00 [medline]
AID - S1083-8791(13)00145-6 [pii]
AID - 10.1016/j.bbmt.2013.03.018 [doi]
PST - ppublish
SO  - Biol Blood Marrow Transplant. 2013 Aug;19(8):1152-8. doi: 
      10.1016/j.bbmt.2013.03.018. Epub 2013 Apr 6.