PMID- 23574844
OWN - NLM
STAT- MEDLINE
DCOM- 20130624
LR  - 20130411
IS  - 1555-9823 (Electronic)
IS  - 0003-1348 (Linking)
VI  - 79
IP  - 4
DP  - 2013 Apr
TI  - Outcomes of laparoscopic Nissen fundoplication in patients with manometric 
      patterns of esophageal motility disorders.
PG  - 361-5
AB  - The manometric pattern of either diffuse esophageal spasm (DES), nutcracker 
      esophagus (NE), or hypertensive lower esophageal sphincter (HLES) in the presence 
      of gastroesophageal reflux disease (GERD) is considered a secondary finding and 
      treatment should be directed toward GERD. This study aims to evaluate the 
      outcomes of laparoscopic Nissen fundoplication (LNF) in patients with manometric 
      patterns of esophageal motility disorders. Patients with GERD confirmed by pH 
      monitoring and manometric pattern of DES (simultaneous contractions 20 to 90% of 
      wet swallows), NE (increased mean distal amplitude greater than 180 mmHg), or 
      HLES (lower esophageal sphincter pressure greater than 45 mmHg) who underwent LNF 
      were studied. A group of 50 consecutive patients with normal esophageal motility 
      who underwent LNF were used as control subjects. Groups were comparable to 
      control subjects for age, gender, preoperative symptoms, hiatal hernia, and 
      Barrett's esophagus, except for NE that had younger individuals and a lower rate 
      of hiatal hernia. Symptomatic outcome was similar when groups were compared with 
      control subjects. Transient dysphagia was present in the postoperative period in 
      33, 7, 0, and 20 per cent of the patients with HLES, DES, NE, and control 
      subjects, respectively. LNF is an adequate treatment for patients with GERD and 
      manometric patterns of esophageal motility disorders.
FAU - Dell'Acqua-Cassao, Bruna
AU  - Dell'Acqua-Cassao B
AD  - Department of Surgery, Escola Paulista de Medicina, Federal University of Sao 
      Paulo, Sao Paulo, Brazil.
FAU - Mardiros-Herbella, Fernando Augusto
AU  - Mardiros-Herbella FA
FAU - Farah, Jose F
AU  - Farah JF
FAU - Bonadiman, Adorisio
AU  - Bonadiman A
FAU - Silva, Luciana C
AU  - Silva LC
FAU - Patti, Marco G
AU  - Patti MG
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am Surg
JT  - The American surgeon
JID - 0370522
SB  - IM
MH  - Esophageal Motility Disorders/physiopathology/*surgery
MH  - Female
MH  - *Fundoplication/methods
MH  - Gastroesophageal Reflux/*complications/surgery
MH  - Humans
MH  - Laparoscopy
MH  - Male
MH  - Manometry
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Treatment Outcome
EDAT- 2013/04/12 06:00
MHDA- 2013/06/26 06:00
CRDT- 2013/04/12 06:00
PHST- 2013/04/12 06:00 [entrez]
PHST- 2013/04/12 06:00 [pubmed]
PHST- 2013/06/26 06:00 [medline]
PST - ppublish
SO  - Am Surg. 2013 Apr;79(4):361-5.