PMID- 23584757
OWN - NLM
STAT- MEDLINE
DCOM- 20140210
LR  - 20211021
IS  - 1861-0692 (Electronic)
IS  - 1861-0684 (Linking)
VI  - 102
IP  - 7
DP  - 2013 Jul
TI  - Mobile left ventricular thrombus in left ventricular dysfunction: case report and 
      review of literature.
PG  - 479-84
LID - 10.1007/s00392-013-0565-2 [doi]
AB  - INTRODUCTION: Left ventricular (LV) thrombi carry a high risk of embolization. 
      Therapeutic recommendations like treatment with low molecular heparin and 
      intravenous unfractionated heparin (UFH), thrombolysis or surgical thrombectomy 
      have failed to reach a consensus. CASE DESCRIPTION: A 56-year-old female patient 
      presented in cardiogenic shock to the emergency department. Echocardiography 
      demonstrated a dilated LV with a severely depressed global systolic function and 
      a large LV apical thrombus. Treatment with UFH was initiated as well as a 
      treatment with catecholamines for stabilizing the patient's hemodynamic 
      situation. On the follow-up echocardiographic examination, extensive 
      free-floating parts of the thrombus could be documented. Given the high risk of 
      embolization in a now hemodynamically stable situation, emergency surgical 
      embolectomy was performed. DISCUSSION: A conservative procedure might be useful 
      for bridging till surgical treatment is available and/or the risk due to surgery 
      is acceptable. CONCLUSION: In absence of evidence-based guidelines for the 
      treatment of LV thrombi, individualized management options concerning surgical, 
      embolization and bleeding risk must be taken into account.
FAU - Leick, Jurgen
AU  - Leick J
AD  - Department of Cardiology, Kerckhoff Heart and Thorax Center, Benekestr. 2-8, 
      61231 Bad Nauheim, Germany.
FAU - Szardien, Sebastian
AU  - Szardien S
FAU - Liebetrau, Christoph
AU  - Liebetrau C
FAU - Willmer, Matthias
AU  - Willmer M
FAU - Fischer-Rasokat, Ulrich
AU  - Fischer-Rasokat U
FAU - Kempfert, Jorg
AU  - Kempfert J
FAU - Nef, Holger
AU  - Nef H
FAU - Rolf, Andreas
AU  - Rolf A
FAU - Walther, Thomas
AU  - Walther T
FAU - Hamm, Christian
AU  - Hamm C
FAU - Mollmann, Helge
AU  - Mollmann H
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20130414
PL  - Germany
TA  - Clin Res Cardiol
JT  - Clinical research in cardiology : official journal of the German Cardiac Society
JID - 101264123
RN  - 0 (Anticoagulants)
RN  - 0 (Catecholamines)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - Anticoagulants/therapeutic use
MH  - Catecholamines/therapeutic use
MH  - Echocardiography
MH  - Embolectomy/methods
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Ventricles/pathology
MH  - Heparin/therapeutic use
MH  - Humans
MH  - Middle Aged
MH  - Shock, Cardiogenic/*etiology/physiopathology
MH  - Thrombosis/diagnosis/*pathology/surgery
MH  - Ventricular Dysfunction, Left/*etiology/surgery
EDAT- 2013/04/16 06:00
MHDA- 2014/02/11 06:00
CRDT- 2013/04/16 06:00
PHST- 2012/10/29 00:00 [received]
PHST- 2013/04/03 00:00 [accepted]
PHST- 2013/04/16 06:00 [entrez]
PHST- 2013/04/16 06:00 [pubmed]
PHST- 2014/02/11 06:00 [medline]
AID - 10.1007/s00392-013-0565-2 [doi]
PST - ppublish
SO  - Clin Res Cardiol. 2013 Jul;102(7):479-84. doi: 10.1007/s00392-013-0565-2. Epub 
      2013 Apr 14.