PMID- 23591533
OWN - NLM
STAT- MEDLINE
DCOM- 20140205
LR  - 20220321
IS  - 1539-2864 (Electronic)
IS  - 0275-004X (Linking)
VI  - 33
IP  - 8
DP  - 2013 Sep
TI  - Using spectral-domain optical coherence tomography imaging to identify the 
      presence of retinal silicone oil emulsification after silicone oil tamponade.
PG  - 1567-73
LID - 10.1097/IAE.0b013e318287d9ea [doi]
AB  - PURPOSE: To describe small hyperreflective areas using spectral-domain optical 
      coherence tomography (SD-OCT) imaging in eyes that have had silicone oil 
      tamponade. METHODS: Retrospective case series of 11 eyes of 11 patients. The 
      authors retrospectively identified patients who underwent vitrectomy and silicone 
      oil tamponade secondary to a rhegmatogenous retinal detachment (nine patients), 
      panuveitis with retinal necrosis (one patient), or recurrent full-thickness 
      macular hole surgery (one patient) who had manifestations of silicone oil 
      emulsion on SD-OCT imaging. Patients were monitored during the postoperative 
      period by clinical examination and using SD-OCT. A model eye in which emulsified 
      silicone oil had been injected in the anterior chamber was used to obtain 
      anterior segment SD-OCT images for comparison. RESULTS: The mean age of our 
      patients was 50 years (range, 39-76 years). In eight eyes, the SD-OCT examination 
      was carried out after silicone oil removal, and in three eyes, the SD-OCT 
      examination was carried out with the oil in situ. Of the nine eyes treated for 
      rhegmatogenous retinal detachment, five had a relieving retinectomy for advanced 
      anterior proliferative vitreoretinopathy or for traumatic retinal incarceration 
      (one eye). The eye treated for full-thickness macular hole had a vitrectomy, 
      internal limiting membrane peel, and silicone oil injection for recurrent macular 
      hole. Ten eyes showed hyperreflective, spherical, tiny droplets using SD-OCT 
      imaging. These were thought to represent silicone oil droplets intraretinally or 
      underneath epiretinal membranes, and one eye showed hyperreflective areas 
      subretinally (retina detached). One additional patient was found to have tiny 
      intravitreal silicone oil droplets after silicone oil removal. Similarly, the 
      silicone oil appeared as multiple hyperreflective spherical droplets as detected 
      by SD-OCT. Anterior segment studies of silicone oil emulsification in the 
      experimental model revealed a similar appearance to that seen with in vivo SD-OCT 
      imaging. CONCLUSION: The authors have found small hyperreflective areas 
      intraretinally, subretinally, and underneath epiretinal membranes on SD-OCT in 
      eyes that have had silicone oil tamponade for a variety of indications. The 
      authors have seen a similar appearance when silicone oil emulsification is 
      examined in vivo. The authors conclude that the hyperreflective areas are likely 
      (but not certain) to be very small bubbles of emulsified silicone. Further 
      studies are required to determine the incidence, clinicopathologic, and 
      functional significance of probable silicone oil emulsification and deposition 
      within the retinal layers.
FAU - Errera, Marie-Helene
AU  - Errera MH
AD  - Moorfields Eye Hospital, London, United Kingdom.
FAU - Liyanage, Sidath E
AU  - Liyanage SE
FAU - Elgohary, Mostafa
AU  - Elgohary M
FAU - Day, Alexander C
AU  - Day AC
FAU - Wickham, Louisa
AU  - Wickham L
FAU - Patel, Praveen J
AU  - Patel PJ
FAU - Sahel, Jose-Alain
AU  - Sahel JA
FAU - Paques, Michel
AU  - Paques M
FAU - Ezra, Eric
AU  - Ezra E
FAU - Sullivan, Paul M
AU  - Sullivan PM
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Retina
JT  - Retina (Philadelphia, Pa.)
JID - 8309919
RN  - 0 (Emulsions)
RN  - 0 (Silicone Oils)
SB  - IM
CIN - Retina. 2014 May;34(5):e13-4. PMID: 24751951
CIN - Retina. 2014 May;34(5):e14. PMID: 24751952
MH  - Adult
MH  - Aged
MH  - *Emulsions
MH  - Endotamponade/*methods
MH  - Epiretinal Membrane/pathology
MH  - Female
MH  - Humans
MH  - Male
MH  - Microbubbles
MH  - Middle Aged
MH  - Postoperative Complications/*diagnosis
MH  - Retinal Detachment/surgery
MH  - Retinal Perforations/surgery
MH  - Retrospective Studies
MH  - *Silicone Oils
MH  - *Tomography, Optical Coherence
MH  - Vitrectomy/*methods
MH  - Vitreous Body/*pathology
EDAT- 2013/04/18 06:00
MHDA- 2014/02/06 06:00
CRDT- 2013/04/18 06:00
PHST- 2013/04/18 06:00 [entrez]
PHST- 2013/04/18 06:00 [pubmed]
PHST- 2014/02/06 06:00 [medline]
AID - 10.1097/IAE.0b013e318287d9ea [doi]
PST - ppublish
SO  - Retina. 2013 Sep;33(8):1567-73. doi: 10.1097/IAE.0b013e318287d9ea.