PMID- 23593531
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130418
LR  - 20211021
IS  - 1948-9358 (Print)
IS  - 1948-9358 (Electronic)
IS  - 1948-9358 (Linking)
VI  - 4
IP  - 2
DP  - 2013 Apr 15
TI  - Bariatric surgery as a treatment option in patients with type 2 diabetes 
      mellitus.
PG  - 14-8
LID - 10.4239/wjd.v4.i2.14 [doi]
AB  - Type 2 diabetes mellitus (T2DM) is a leading cause of blindness, non-traumatic 
      amputation and end-stage renal disease as well as a major cardiovascular risk 
      factor. Tight glycemic control reduces the incidence of microvascular 
      complications of T2DM whereas its effects on macrovascular complication are more 
      controversial. However, glycemic targets are achieved by a minority of diabetic 
      patients despite the availability of several antidiabetic agents. In the present 
      commentary, we discuss the findings of two recent randomized studies that 
      compared bariatric surgery with medical treatment in patients with uncontrolled 
      T2DM. Both studies showed that bariatric surgery results in remission of T2DM in 
      the majority of patients. However, both studies were limited to relatively young 
      patients without comorbidities, had relatively short follow-up and did not assess 
      the effects of surgery on T2DM complications. Moreover, the perioperative 
      complications of bariatric surgery and its limited availability in some areas are 
      additional barriers to the wider implementation of this therapeutic approach. On 
      the other hand, the elucidation of the mechanisms underpinning the resolution of 
      T2DM following bariatric surgery might result in the development of novel, more 
      effective pharmacotherapies for this common disease.
FAU - Spanou, Marianna
AU  - Spanou M
AD  - Marianna Spanou, Konstantinos Tziomalos, First Propedeutic Department of Internal 
      Medicine, Medical School, AHEPA Hospital, Aristotle University of Thessaloniki, 
      54636 Thessaloniki, Greece.
FAU - Tziomalos, Konstantinos
AU  - Tziomalos K
LA  - eng
PT  - Journal Article
PL  - United States
TA  - World J Diabetes
JT  - World journal of diabetes
JID - 101547524
PMC - PMC3627414
OTO - NOTNLM
OT  - Adjustable gastric banding
OT  - Bariatric surgery
OT  - Biliopancreatic diversion
OT  - Roux-en-Y gastric bypass
OT  - Sleeve gastrectomy
OT  - Type 2 diabetes mellitu
EDAT- 2013/04/18 06:00
MHDA- 2013/04/18 06:01
PMCR- 2013/04/15
CRDT- 2013/04/18 06:00
PHST- 2012/12/23 00:00 [received]
PHST- 2013/02/10 00:00 [revised]
PHST- 2013/03/06 00:00 [accepted]
PHST- 2013/04/18 06:00 [entrez]
PHST- 2013/04/18 06:00 [pubmed]
PHST- 2013/04/18 06:01 [medline]
PHST- 2013/04/15 00:00 [pmc-release]
AID - 10.4239/wjd.v4.i2.14 [doi]
PST - ppublish
SO  - World J Diabetes. 2013 Apr 15;4(2):14-8. doi: 10.4239/wjd.v4.i2.14.