PMID- 23611536 OWN - NLM STAT- MEDLINE DCOM- 20140512 LR - 20220408 IS - 1573-2517 (Electronic) IS - 0165-0327 (Linking) VI - 150 IP - 3 DP - 2013 Sep 25 TI - The societal cost of depression: evidence from 10,000 Swedish patients in psychiatric care. PG - 790-7 LID - S0165-0327(13)00227-9 [pii] LID - 10.1016/j.jad.2013.03.003 [doi] AB - OBJECTIVE: Depression cost studies have mainly taken a primary care perspective and should be completed with cost estimates from psychiatric care. The objectives of this study were to estimate the societal per-patient cost of depression in specialized psychiatric care in Sweden, and to relate costs to disease severity, depressive episodes, hospitalization, and patient functioning. METHODS: Retrospective resource use data in inpatient and outpatient care for 2006-2008, as well as ICD-10 diagnoses and Global Assessment of Functioning (GAF), were obtained from the Northern Stockholm psychiatric clinic (covering half of Stockholm's population aged 18 years and above). As a complement, data from national registers on pharmaceuticals and sick leave were used in order to estimate the societal cost of depression. RESULTS: Based on 10,430 patients (63% women), the mean annual per-patient cost was euro17,279 in 2008. The largest cost item was indirect costs due to productivity losses (88%), followed by outpatient care (6%). Patients with mild and severe depression had average costs of euro14,200 and euro21,500, respectively. Total costs were substantially higher during depressive episodes, among patients with co-morbid psychosis or anxiety, for hospitalized patients, and for patients with poor functioning. LIMITATIONS: Primary care costs and costs for reduced productivity at work were not included. CONCLUSIONS: The main cost item among depression patients in psychiatric care was indirect costs. Costs were higher than previously reported for primary care, and strongly related to hospitalization, depressive episodes, and low functioning. This suggests that effective treatment that avoids depressive episodes and hospitalization may reduce society's costs for depression. CI - (c) 2013 Elsevier B.V. All rights reserved. FAU - Ekman, M AU - Ekman M AD - OptumInsight, Stockholm, Sweden. mattias.ekman@astrazeneca.com FAU - Granstrom, O AU - Granstrom O FAU - Omerov, S AU - Omerov S FAU - Jacob, J AU - Jacob J FAU - Landen, M AU - Landen M LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130421 PL - Netherlands TA - J Affect Disord JT - Journal of affective disorders JID - 7906073 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Ambulatory Care/economics MH - Comorbidity MH - *Cost of Illness MH - Depressive Disorder, Major/*economics MH - Female MH - Health Care Costs MH - Health Resources/economics MH - Hospitalization/economics MH - Humans MH - International Classification of Diseases/standards MH - Male MH - Middle Aged MH - Primary Health Care/economics MH - Retrospective Studies MH - Sick Leave/economics MH - Sweden/epidemiology MH - Young Adult OTO - NOTNLM OT - Burden-of-illness OT - Cost OT - Depression OT - Resource use EDAT- 2013/04/25 06:00 MHDA- 2014/05/13 06:00 CRDT- 2013/04/25 06:00 PHST- 2012/10/22 00:00 [received] PHST- 2013/03/04 00:00 [revised] PHST- 2013/03/06 00:00 [accepted] PHST- 2013/04/25 06:00 [entrez] PHST- 2013/04/25 06:00 [pubmed] PHST- 2014/05/13 06:00 [medline] AID - S0165-0327(13)00227-9 [pii] AID - 10.1016/j.jad.2013.03.003 [doi] PST - ppublish SO - J Affect Disord. 2013 Sep 25;150(3):790-7. doi: 10.1016/j.jad.2013.03.003. Epub 2013 Apr 21.