PMID- 23622205
OWN - NLM
STAT- MEDLINE
DCOM- 20140401
LR  - 20130429
IS  - 0072-9752 (Print)
IS  - 0072-9752 (Linking)
VI  - 111
DP  - 2013
TI  - Idiopathic generalized epilepsies.
PG  - 579-89
LID - B978-0-444-52891-9.00060-9 [pii]
LID - 10.1016/B978-0-444-52891-9.00060-9 [doi]
AB  - Idiopathic generalized epilepsies (IGEs) may start in infancy, childhood, or 
      adolescence, but some have an onset in adulthood. They are genetically determined 
      and affect otherwise healthy people of both sexes and all races, and are 
      generally lifelong. Some, however, are age related. IGEs account for nearly a 
      third of all epilepsies. According to the International League Against Epilepsy 
      (ILAE) proposed classification, the following IGEs are recognized in accordance 
      with the age at onset (Engel, 2001): benign myoclonic epilepsy in infancy (BMEI), 
      generalized epilepsies with febrile seizures plus (GEFS+), epilepsy with 
      myoclonic-astatic seizures (EMAS), epilepsy with myoclonic absences (EMA), 
      childhood absence epilepsy (CAE), and IGEs with variable phenotypes (IGEVP) that 
      include juvenile absence epilepsy (JAE), juvenile myoclonic epilepsy (JME), and 
      epilepsy with generalized tonic-clonic seizures only (EGTCSO). These IGEs raise a 
      conceptual issue since some conditions are epilepsy syndromes (a combination of a 
      given age of onset, seizure type(s), and interictal and clinical and EEG 
      features) (i.e., BMEI, EMAS, EMA, CAE, JAE, JME) whereas others join several 
      types of epilepsy in a given family (i.e., GEFS+and eventually IGEVP and EGTCSO). 
      This chapter describes the electroclinical features, evolution, and therapeutic 
      aspects of IGEs.
CI  - Copyright (c) 2013 Elsevier B.V. All rights reserved.
FAU - Caraballo, Roberto H
AU  - Caraballo RH
AD  - Neurology Service, Hospital de Pediatria "Prof. Dr. Juan P Garrahan," Buenos 
      Aires, Argentina. Electronic address: rhcaraballo@arnet.com.ar.
FAU - Dalla Bernardina, Bernardo
AU  - Dalla Bernardina B
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Netherlands
TA  - Handb Clin Neurol
JT  - Handbook of clinical neurology
JID - 0166161
SB  - IM
MH  - Brain Waves/physiology
MH  - Diagnosis, Differential
MH  - Electroencephalography
MH  - *Epilepsy, Generalized/diagnosis/epidemiology/therapy
MH  - Humans
EDAT- 2013/04/30 06:00
MHDA- 2014/04/02 06:00
CRDT- 2013/04/30 06:00
PHST- 2013/04/30 06:00 [entrez]
PHST- 2013/04/30 06:00 [pubmed]
PHST- 2014/04/02 06:00 [medline]
AID - B978-0-444-52891-9.00060-9 [pii]
AID - 10.1016/B978-0-444-52891-9.00060-9 [doi]
PST - ppublish
SO  - Handb Clin Neurol. 2013;111:579-89. doi: 10.1016/B978-0-444-52891-9.00060-9.