PMID- 23635309
OWN - NLM
STAT- MEDLINE
DCOM- 20140626
LR  - 20220316
IS  - 1743-6109 (Electronic)
IS  - 1743-6095 (Linking)
VI  - 10
IP  - 7
DP  - 2013 Jul
TI  - Comparing effects of low- and high-volume moderate-intensity exercise on sexual 
      function and testosterone in obese men.
PG  - 1823-32
LID - 10.1111/jsm.12154 [doi]
AB  - INTRODUCTION: Obesity and inactivity are associated with erectile dysfunction and 
      hypogonadism. AIM: To compare the effects of low volume (LV) and high volume (HV) 
      of moderate-intensity exercise on sexual function, testosterone, lower urinary 
      tract symptoms (LUTS), endothelial function, and quality of life (QoL) in obese 
      men. MAIN OUTCOME MEASURES: Weight, waist circumference (WC), body composition, 
      International Index of Erectile Function 5-item (IIEF-5), International Prostate 
      Symptom Scale (IPSS) (for LUTS), and 36-item Short Form Survey version 2 
      Instrument (SF-36) (for QoL) scores, plasma testosterone, sex-hormone binding 
      globulin, glucose, insulin and lipids, and endothelial function (by Reactive 
      Hyperaemia Index [RHI] using finger plethysmography) were measured at baseline 
      and 24 weeks. METHODS: Ninety abdominally obese (body mass index > 27.5 kg/m(2), 
      WC > 90 cm), sedentary (exercise  approximately  80 minutes/week) Asian men (mean age 43.6 
      years, range 30-60) were prescribed a diet to reduce daily intake by  approximately  400 kcal 
      below calculated requirement and randomized to perform moderate-intensity 
      exercise of LV (<150 minutes/week) or HV (200-300 minutes/week) (n = 45 each) for 
      24 weeks. Seventy-five men (83.3%) completed the study. RESULTS: Weekly exercise 
      volume was significantly greater in the HV (236 +/- 9 minutes) than the LV (105 +/- 9 
      minutes) group. The HV group had significantly greater increases in IIEF-5 score 
      (2.6 +/- 0.5 points) and testosterone (2.06 +/- 0.46 nmol/L) and reductions in weight 
      (-5.9 +/- 0.7 kg, -6.2%), WC (-4.9 +/- 0.8 cm, -4.9%), and fat mass (-4.7 +/- 1.0 kg, 
      -14.5%) than the LV group (-2.9 +/- 0.7 kg, -3.0%; -2.7 +/- 0.7 cm, -2.5%; -1.1 +/- 0.8 
      kg, -3.2%; 0.79 +/- 0.46 nmol/L; and 1.8 +/- 0.5 points). Improvements in IPSS and 
      SF-36 scores, and RHI, were similar. CONCLUSIONS: Moderate-intensity HV aerobic 
      exercise > 200 minutes/week produces greater improvements in sexual function, 
      testosterone, weight, WC, and fat mass than smaller exercise volume.
CI  - (c) 2013 International Society for Sexual Medicine.
FAU - Khoo, Joan
AU  - Khoo J
AD  - Department of Endocrinology, Changi General Hospital, Singapore, Singapore. 
      joan_khoo@cgh.com.sg
FAU - Tian, Ho-Heng
AU  - Tian HH
FAU - Tan, Benedict
AU  - Tan B
FAU - Chew, Kelvin
AU  - Chew K
FAU - Ng, Chung-Sien
AU  - Ng CS
FAU - Leong, Darren
AU  - Leong D
FAU - Teo, Raymond Choon-Chye
AU  - Teo RC
FAU - Chen, Richard Yuan-Tud
AU  - Chen RY
LA  - eng
SI  - ClinicalTrials.gov/NCT01554735
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, Non-U.S. Gov't
DEP - 20130501
PL  - Netherlands
TA  - J Sex Med
JT  - The journal of sexual medicine
JID - 101230693
RN  - 0 (Sex Hormone-Binding Globulin)
RN  - 3XMK78S47O (Testosterone)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Body Composition
MH  - Body Mass Index
MH  - Body Weight
MH  - Erectile Dysfunction/etiology/*therapy
MH  - *Exercise
MH  - Humans
MH  - Male
MH  - Obesity/complications/*therapy
MH  - Prostate/physiopathology
MH  - Quality of Life
MH  - Sex Hormone-Binding Globulin
MH  - Testosterone/*blood
MH  - Waist Circumference
OTO - NOTNLM
OT  - Erectile Dysfunction
OT  - LUTS
OT  - Obesity
OT  - Regular Physical Exercise
OT  - Weight Loss
EDAT- 2013/05/03 06:00
MHDA- 2014/06/27 06:00
CRDT- 2013/05/03 06:00
PHST- 2013/05/03 06:00 [entrez]
PHST- 2013/05/03 06:00 [pubmed]
PHST- 2014/06/27 06:00 [medline]
AID - S1743-6095(15)30417-3 [pii]
AID - 10.1111/jsm.12154 [doi]
PST - ppublish
SO  - J Sex Med. 2013 Jul;10(7):1823-32. doi: 10.1111/jsm.12154. Epub 2013 May 1.