PMID- 2363838
OWN - NLM
STAT- MEDLINE
DCOM- 19900813
LR  - 20191210
IS  - 0166-4328 (Print)
IS  - 0166-4328 (Linking)
VI  - 38
IP  - 2
DP  - 1990 May 7
TI  - Classical nictitating membrane conditioning in rabbits with varying interstimulus 
      intervals and direct activation of cerebellar mossy fibers as the CS.
PG  - 97-108
AB  - The rate and level of classical nictitating membrane (NM)/eyelid conditioning in 
      rabbits established by pairing a pontine nucleus stimulation conditioned stimulus 
      (CS) with an air puff unconditioned stimulus (US) were studied at 6 interstimulus 
      intervals (ISIs). Similar to earlier studies which used peripheral CSs, an 
      inverted U-shaped function relating ISI and conditioning was generated. 
      Interstimulus intervals of 250 and 500 ms produced the highest levels of 
      conditioning, 100, 1000 and 2000 ms ISIs resulted in lower levels of 
      conditioning, and no conditioning was established with a 50 ms ISI. These results 
      demonstrate that a normal ISI function can be established when direct activation 
      of cerebellar mossy fibers is used as a CS instead of conventional peripheral 
      CSs.
FAU - Steinmetz, J E
AU  - Steinmetz JE
AD  - Department of Psychology, Indiana University, Bloomington 47405.
LA  - eng
GR  - MH44052/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Behav Brain Res
JT  - Behavioural brain research
JID - 8004872
SB  - IM
MH  - Animals
MH  - Arousal/*physiology
MH  - Association Learning/*physiology
MH  - Attention/physiology
MH  - Brain Mapping
MH  - Cerebellum/*physiology
MH  - Conditioning, Eyelid/*physiology
MH  - Learning/*physiology
MH  - Male
MH  - Nerve Fibers/*physiology
MH  - Neural Pathways/physiology
MH  - Pons/physiology
MH  - Rabbits
MH  - Reaction Time/*physiology
MH  - Retention, Psychology/physiology
EDAT- 1990/05/07 00:00
MHDA- 1990/05/07 00:01
CRDT- 1990/05/07 00:00
PHST- 1990/05/07 00:00 [pubmed]
PHST- 1990/05/07 00:01 [medline]
PHST- 1990/05/07 00:00 [entrez]
AID - 0166-4328(90)90008-3 [pii]
AID - 10.1016/0166-4328(90)90008-3 [doi]
PST - ppublish
SO  - Behav Brain Res. 1990 May 7;38(2):97-108. doi: 10.1016/0166-4328(90)90008-3.