PMID- 23639203
OWN - NLM
STAT- MEDLINE
DCOM- 20131210
LR  - 20130520
IS  - 1520-510X (Electronic)
IS  - 0020-1669 (Linking)
VI  - 52
IP  - 10
DP  - 2013 May 20
TI  - General strategy for the synthesis of rigid weak-link approach platinum(II) 
      complexes: tweezers, triple-layer complexes, and macrocycles.
PG  - 5876-88
LID - 10.1021/ic302855f [doi]
AB  - Air-stable, heteroligated platinum(II) weak-link approach (WLA) tweezer and 
      triple-layer complexes that possess P,X-Aryl hemilabile ligands (P; = 
      Ph2PCH2CH2-, X = chalcoethers or amines) have been synthesized via the 
      halide-induced ligand rearrangement (HILR) reaction, using a one-pot, partial 
      chloride-abstraction method. The approach is general and works with a variety of 
      phosphine-based hemilabile ligands; when a P,S-Ph ligand is used as the 
      relatively strongly chelating ligand, heteroligated complexes are formed cleanly 
      when an ether- (P,O-Ph), amine- (P,N-Ph2), or fluorinated thioether-based 
      (P,S-C6F4H) hemilabile ligand is used as the weakly chelating counterpart. The 
      HILR reaction has also been used to synthesize bisplatinum(II) macrocycles free 
      of oligomeric material without having to resort to the high-dilution conditions 
      typical for macrocycle synthesis. This approach is complementary to the 
      traditional WLA to the synthesis of macrocyclic complexes which typically 
      proceeds via fully closed, chloride-free intermediates. The structures of the 
      complexes may be toggled between semiopen (with only one chelating ligand) and 
      fully closed (with both ligands chelating) via the abstraction and addition of 
      chloride.
FAU - Kennedy, Robert D
AU  - Kennedy RD
AD  - Department of Chemistry and International Institute for Nanotechnology, 
      Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208, United 
      States.
FAU - Machan, Charles W
AU  - Machan CW
FAU - McGuirk, C Michael
AU  - McGuirk CM
FAU - Rosen, Mari S
AU  - Rosen MS
FAU - Stern, Charlotte L
AU  - Stern CL
FAU - Sarjeant, Amy A
AU  - Sarjeant AA
FAU - Mirkin, Chad A
AU  - Mirkin CA
LA  - eng
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20130502
PL  - United States
TA  - Inorg Chem
JT  - Inorganic chemistry
JID - 0366543
RN  - 0 (Macrocyclic Compounds)
RN  - 0 (Organoplatinum Compounds)
SB  - IM
MH  - Crystallography, X-Ray
MH  - Macrocyclic Compounds/*chemical synthesis/chemistry
MH  - Models, Molecular
MH  - Molecular Structure
MH  - Organoplatinum Compounds/*chemical synthesis/chemistry
EDAT- 2013/05/04 06:00
MHDA- 2013/12/16 06:00
CRDT- 2013/05/04 06:00
PHST- 2013/05/04 06:00 [entrez]
PHST- 2013/05/04 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
AID - 10.1021/ic302855f [doi]
PST - ppublish
SO  - Inorg Chem. 2013 May 20;52(10):5876-88. doi: 10.1021/ic302855f. Epub 2013 May 2.