PMID- 23639992 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20131209 LR - 20130522 IS - 1473-0189 (Electronic) IS - 1473-0189 (Linking) VI - 13 IP - 12 DP - 2013 Jun 21 TI - Microfluidics on liquid handling stations (muF-on-LHS): an industry compatible chip interface between microfluidics and automated liquid handling stations. PG - 2337-43 LID - 10.1039/c3lc00042g [doi] AB - We describe a generic microfluidic interface design that allows the connection of microfluidic chips to established industrial liquid handling stations (LHS). A molding tool has been designed that allows fabrication of low-cost disposable polydimethylsiloxane (PDMS) chips with interfaces that provide convenient and reversible connection of the microfluidic chip to industrial LHS. The concept allows complete freedom of design for the microfluidic chip itself. In this setup all peripheral fluidic components (such as valves and pumps) usually required for microfluidic experiments are provided by the LHS. Experiments (including readout) can be carried out fully automated using the hardware and software provided by LHS manufacturer. Our approach uses a chip interface that is compatible with widely used and industrially established LHS which is a significant advancement towards near-industrial experimental design in microfluidics and will greatly facilitate the acceptance and translation of microfluidics technology in industry. FAU - Waldbaur, Ansgar AU - Waldbaur A AD - Institute of Microstructure Technology (IMT), KIT, Eggenstein-Leopoldshafen, Germany. FAU - Kittelmann, Jorg AU - Kittelmann J FAU - Radtke, Carsten P AU - Radtke CP FAU - Hubbuch, Jurgen AU - Hubbuch J FAU - Rapp, Bastian E AU - Rapp BE LA - eng PT - Journal Article DEP - 20130503 PL - England TA - Lab Chip JT - Lab on a chip JID - 101128948 EDAT- 2013/05/04 06:00 MHDA- 2013/05/04 06:01 CRDT- 2013/05/04 06:00 PHST- 2013/05/04 06:00 [entrez] PHST- 2013/05/04 06:00 [pubmed] PHST- 2013/05/04 06:01 [medline] AID - 10.1039/c3lc00042g [doi] PST - ppublish SO - Lab Chip. 2013 Jun 21;13(12):2337-43. doi: 10.1039/c3lc00042g. Epub 2013 May 3.