PMID- 23646115 OWN - NLM STAT- MEDLINE DCOM- 20131126 LR - 20211021 IS - 1932-6203 (Electronic) IS - 1932-6203 (Linking) VI - 8 IP - 4 DP - 2013 TI - Association between ambient temperature and acute myocardial infarction hospitalisations in Gothenburg, Sweden: 1985-2010. PG - e62059 LID - 10.1371/journal.pone.0062059 [doi] LID - e62059 AB - Cardiovascular disease (CVD) is the number one cause of death globally and evidence is steadily increasing on the role of non-traditional risk factors such as meteorology and air pollution. Nevertheless, many research gaps remain, such as the association between these non-traditional risk factors and subtypes of CVD, such as acute myocardial infarction (AMI). The objective of this study was to investigate the association between daily ambient temperature and AMI hospitalisations using a case-crossover design in Gothenburg, Sweden (1985-2010). A secondary analysis was also performed for out-of-hospital ischemic heart disease (IHD) deaths. Susceptible groups by age and sex were explored. The entire year as well as the warm (April-September) and cold periods (October-March) were considered. In total 28,215 AMI hospitalisations (of 22,475 people) and 21,082 out-of-hospital IHD deaths occurred during the 26-year study period. A linear exposure-response corresponding to a 3% and 7% decrease in AMI hospitalisations was observed for an inter-quartile range (IQR) increase in the 2-day cumulative average of temperature during the entire year (11 degrees C) and the warm period (6 degrees C), respectively, with and without adjustment for PM(1)(0), NO(2), NOx or O(3). No heat waves occurred during the warm period. No evidence of an association in the cold period nor any association between temperature and IHD deaths in the entire year, warm or cold periods--with and without adjusting for PM(1)(0), NO(2), NOx or O(3) was found. No susceptible groups, based on age or sex, were identified either. The inverse association between temperature and AMI hospitalisations (entire year and warm period) in Gothenburg is in accordance with the majority of the few other studies that investigated this subtype of CVD. FAU - Wichmann, Janine AU - Wichmann J AD - Department of Occupational and Environmental Medicine, Sahlgrenska University Hospital and University of Gothenburg, Gothenborg, Sweden. gerd.sallsten@amm.gu.se FAU - Rosengren, Annika AU - Rosengren A FAU - Sjoberg, Karin AU - Sjoberg K FAU - Barregard, Lars AU - Barregard L FAU - Sallsten, Gerd AU - Sallsten G LA - eng PT - Historical Article PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20130430 PL - United States TA - PLoS One JT - PloS one JID - 101285081 RN - 0 (Air Pollutants) SB - IM MH - Adult MH - Age Factors MH - Air Pollutants/analysis MH - Air Pollution MH - Female MH - History, 20th Century MH - History, 21st Century MH - Hospital Mortality MH - *Hospitalization MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/*epidemiology/*etiology/history MH - Patient Admission MH - Risk Factors MH - Seasons MH - Sex Factors MH - Sweden/epidemiology MH - *Temperature MH - Young Adult PMC - PMC3639986 COIS- Competing Interests: The authors have declared that no competing interests exist. EDAT- 2013/05/07 06:00 MHDA- 2013/12/16 06:00 PMCR- 2013/04/30 CRDT- 2013/05/07 06:00 PHST- 2012/12/27 00:00 [received] PHST- 2013/03/17 00:00 [accepted] PHST- 2013/05/07 06:00 [entrez] PHST- 2013/05/07 06:00 [pubmed] PHST- 2013/12/16 06:00 [medline] PHST- 2013/04/30 00:00 [pmc-release] AID - PONE-D-13-02504 [pii] AID - 10.1371/journal.pone.0062059 [doi] PST - epublish SO - PLoS One. 2013 Apr 30;8(4):e62059. doi: 10.1371/journal.pone.0062059. Print 2013.