PMID- 23656553
OWN - NLM
STAT- MEDLINE
DCOM- 20140225
LR  - 20131230
IS  - 1600-0463 (Electronic)
IS  - 0903-4641 (Linking)
VI  - 122
IP  - 1
DP  - 2014 Jan
TI  - Microbiology of folliculitis: a histological study of 39 cases.
PG  - 25-32
LID - 10.1111/apm.12103 [doi]
AB  - Folliculitis is a common inflammatory skin syndrome. Several microbial organisms 
      have been put forward as causative agents, but few studies visualized microbes 
      directly in inflamed hair follicles. This retrospective study investigated 
      bacterial and fungal colonization of inflamed hair follicles in patients with 
      clinically diagnosed non-infectious folliculitis. Skin biopsies from 39 
      folliculitis patients and 27 controls were screened by fluorescence in situ 
      hybridization (FISH) using broad-range bacterial and fungal probes and by 
      immunofluorescence microscopy using a monoclonal antibody towards Gram-positive 
      bacteria. Specific monoclonal and polyclonal antibodies towards Staphylococcus 
      spp. and Propionibacterium acnes were applied for further species identification. 
      Inflamed follicles were associated with bacterial colonization in 10 samples 
      (26%) and fungal colonization in three samples (8%). Staphylococcus spp. were 
      observed in inflamed follicles in seven samples (18%). Two samples were positive 
      for P. acnes, which were identified as either type II or type IB/type III. Both 
      Staphylococcus spp. and P. acnes were seen in macrocolonies/biofilm structures. 
      In conclusion, one-third of patients with clinically diagnosed, non-infectious 
      folliculitis exhibited microbial colonization with predominance of Staphylococcus 
      spp.
CI  - (c) 2013 APMIS Published by Blackwell Publishing Ltd.
FAU - Jahns, Anika C
AU  - Jahns AC
AD  - Medical Biosciences/Pathology, Umea University, Umea, Sweden.
FAU - Lundskog, Bertil
AU  - Lundskog B
FAU - Berg, Johanna
AU  - Berg J
FAU - Jonsson, Rebecca
AU  - Jonsson R
FAU - McDowell, Andrew
AU  - McDowell A
FAU - Patrick, Sheila
AU  - Patrick S
FAU - Golovleva, Irina
AU  - Golovleva I
FAU - Palmer, Ruth H
AU  - Palmer RH
FAU - Alexeyev, Oleg A
AU  - Alexeyev OA
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130508
PL  - Denmark
TA  - APMIS
JT  - APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
JID - 8803400
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Case-Control Studies
MH  - Child
MH  - Female
MH  - Folliculitis/*microbiology/pathology
MH  - Fungi/genetics/isolation & purification
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Male
MH  - Microscopy, Fluorescence
MH  - Propionibacterium acnes/isolation & purification
MH  - Retrospective Studies
MH  - Staphylococcus/isolation & purification
MH  - Young Adult
OTO - NOTNLM
OT  - Propionibacterium acnes
OT  - Skin
OT  - Staphylococcus.
OT  - folliculitis
OT  - in situ hybridization
OT  - microbiota
EDAT- 2013/05/10 06:00
MHDA- 2014/02/26 06:00
CRDT- 2013/05/10 06:00
PHST- 2012/11/08 00:00 [received]
PHST- 2013/03/05 00:00 [accepted]
PHST- 2013/05/10 06:00 [entrez]
PHST- 2013/05/10 06:00 [pubmed]
PHST- 2014/02/26 06:00 [medline]
AID - 10.1111/apm.12103 [doi]
PST - ppublish
SO  - APMIS. 2014 Jan;122(1):25-32. doi: 10.1111/apm.12103. Epub 2013 May 8.