PMID- 23667121
OWN - NLM
STAT- MEDLINE
DCOM- 20130830
LR  - 20130513
IS  - 1881-6096 (Print)
IS  - 1881-6096 (Linking)
VI  - 65
IP  - 5
DP  - 2013 May
TI  - [Nonconvulsive status epilepticus: clinical practice and pathophysiology].
PG  - 561-72
AB  - The clinical spectrum of nonconvulsive status epilepticus (NCSE) is rapidly 
      expanding from classical manifestations, such as staring, repetitive blinking, 
      chewing, swallowing, and automatism to novel manifestations, such as acute and 
      protracted coma, apnea, cognitive impairment, higher brain dysfunction, and 
      cardiac arrest. It is only in the last decade that these novel NCSE 
      manifestations have been revealed, which is certainly reflective of modern 
      advances in critical care neurology, such as the introduction and spread of 
      continuous electroencephalography (cEEG) monitoring. Although NCSE is a 
      relatively frequent, treatable condition but with a high mortality rate, 
      physicians are still unfamiliar with its clinical manifestations, thus leading to 
      underdiagnosis. In this review, the clinical manifestations, epidemiology, 
      diagnosis, and management of NCSE are critically described using the best 
      available evidence and perspectives, including my hypothesis on epileptic organ 
      dysfunction; in particular, the possible causal relationship between NCSE and 
      cardiac arrhythmia, such as atrial fibrillation is also discussed.
FAU - Nagayama, Masao
AU  - Nagayama M
AD  - Department of Neurology, International University of Health and Welfare, Japan.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PT  - Review
PL  - Japan
TA  - Brain Nerve
JT  - Brain and nerve = Shinkei kenkyu no shinpo
JID - 101299709
SB  - IM
MH  - Animals
MH  - Cognition Disorders/complications/physiopathology
MH  - Critical Care
MH  - Electroencephalography/methods
MH  - Humans
MH  - Monitoring, Physiologic/methods
MH  - Status Epilepticus/classification/*diagnosis/*physiopathology/therapy
EDAT- 2013/05/15 06:00
MHDA- 2013/08/31 06:00
CRDT- 2013/05/14 06:00
PHST- 2013/05/14 06:00 [entrez]
PHST- 2013/05/15 06:00 [pubmed]
PHST- 2013/08/31 06:00 [medline]
AID - 1416101496 [pii]
PST - ppublish
SO  - Brain Nerve. 2013 May;65(5):561-72.