PMID- 23680280
OWN - NLM
STAT- MEDLINE
DCOM- 20131126
LR  - 20220410
IS  - 1475-2840 (Electronic)
IS  - 1475-2840 (Linking)
VI  - 12
DP  - 2013 May 16
TI  - Neck circumference as an independent predictive contributor to cardio-metabolic 
      syndrome.
PG  - 76
LID - 10.1186/1475-2840-12-76 [doi]
AB  - BACKGROUND: The predictive potentials of neck circumference (NC) for 
      cardio-metabolic risks remain uncertain. The aim of this study was to investigate 
      whether NC independently contributes to the prediction of cardio-metabolic risks 
      beyond body mass index (BMI), waist circumference (WC) and waist to hip ratio 
      (WHpR) in a large Chinese population. METHODS: A total of 4201 participants (2508 
      men and 1693 women) aged 20-85 were recruited from the Health Examination Centre 
      between May 2009 and April 2010, anthropometric indices, biochemical and clinical 
      parameters were measured. Receiver operating characteristic, partial correlation 
      and logistic regression analyses were employed to evaluate the association of the 
      anthropometric indices to cardio-metabolic risks separately by gender. RESULTS: 
      Neck circumference was positively correlated with SBP and DBP (r=0.250 and 
      0.261), fasting blood glucose (FBP) (r=0.177), TG (r=0.240), TC (r=0.143) and 
      LDL-C (r=0.088) and negatively correlated with HDL-C (r=-0.202) in males (all 
      P<0.01). Similar results were found in females with the exception of TC. The AUCs 
      of NC for metabolic abnormalities ranged from 0.558 (Increased LDL-C) to 0.683 
      (MS-rf) in men and 0.596 (Increased LDL-C) to 0.703 (MS-rf) in women (P<0.01). 
      The NC of >/=37 cm for men and >/=33 cm for women were the best cut-off points for 
      metabolic syndrome. The adjusted ORs (95% CIs) of NC in men and women 
      respectively were 1.29 (1.12-1.48) and 1.44 (1.20-1.72) for metabolic syndrome 
      risk factors (MS-rf), 1.15 (1.01-1.32) and 1.22 (1.03-1.46) for high BP, 1.16 
      (1.02-1.33) and 1.42 (1.18-1.71) for increased TG, and 1.26 (1.06-1.50) and 1.32 
      (1.06-1.65) for increased FBP; the adjusted OR of NC in women for decreased HDL-C 
      was 1.29 (1.10-1.51). CONCLUSIONS: Neck circumference was significantly 
      associated with cardio-metabolic risk factors and independently contributed to 
      the prediction of cardio-metabolic risks beyond the classical anthropometric 
      indices in adults of China.
FAU - Zhou, Jing-ya
AU  - Zhou JY
AD  - Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of 
      Public Health, Sun Yat-Sen University, 74th Zhongshan Road II, Guangzhou 510080, 
      People's Republic of China.
FAU - Ge, Hui
AU  - Ge H
FAU - Zhu, Ming-fan
AU  - Zhu MF
FAU - Wang, Li-jun
AU  - Wang LJ
FAU - Chen, Li
AU  - Chen L
FAU - Tan, Yao-zong
AU  - Tan YZ
FAU - Chen, Yu-ming
AU  - Chen YM
FAU - Zhu, Hui-lian
AU  - Zhu HL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130516
PL  - England
TA  - Cardiovasc Diabetol
JT  - Cardiovascular diabetology
JID - 101147637
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Blood Glucose
MH  - Blood Pressure
MH  - Body Mass Index
MH  - *Body Size
MH  - *Cardiovascular Diseases
MH  - Dyslipidemias
MH  - Female
MH  - Humans
MH  - Male
MH  - *Metabolic Syndrome
MH  - Middle Aged
MH  - *Neck
MH  - *Obesity, Abdominal
MH  - ROC Curve
MH  - Risk Assessment
MH  - Risk Factors
MH  - Waist Circumference
MH  - Waist-Hip Ratio
MH  - Young Adult
PMC - PMC3661343
EDAT- 2013/05/18 06:00
MHDA- 2013/12/16 06:00
PMCR- 2013/05/16
CRDT- 2013/05/18 06:00
PHST- 2013/05/11 00:00 [received]
PHST- 2013/05/13 00:00 [accepted]
PHST- 2013/05/18 06:00 [entrez]
PHST- 2013/05/18 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
PHST- 2013/05/16 00:00 [pmc-release]
AID - 1475-2840-12-76 [pii]
AID - 10.1186/1475-2840-12-76 [doi]
PST - epublish
SO  - Cardiovasc Diabetol. 2013 May 16;12:76. doi: 10.1186/1475-2840-12-76.