PMID- 23681897 OWN - NLM STAT- MEDLINE DCOM- 20140108 LR - 20130517 IS - 1439-7803 (Electronic) IS - 0044-2771 (Linking) VI - 51 IP - 5 DP - 2013 May TI - Manifestation of an abdominal immune reconstitution inflammatory syndrome associated with a nontuberculous mycobacterial infection - a case report. PG - 440-3 LID - 10.1055/s-0033-1335012 [doi] AB - Immune reconstitution inflammatory syndrome (IRIS) is an inflammatory reaction in HIV-infected patients after initiation of antiretroviral therapy. It results from restored immunity to specific infectious or non-infectious antigens. We describe the case of a 47-year-old female patient who presented with an unspecific painful pressure in the abdomen and weight loss that was diagnosed as intra-abdominal (unmasking) IRIS due to nontuberculous mycobacterial infection (Mycobacterium avium complex). Antiretroviral therapy had been initiated six months earlier when pneumocystis pneumonia led to the diagnosis of HIV infection with a viral load of 123 000 copies/ml and a CD 4 cell count of 6/microl. Although IRIS is a known complication after initiation of antiretroviral therapy in HIV-infected patients this case with a rare site of manifestation and symptoms that are common in all day gastroenterological clinic highlights a differential diagnosis that requires a high index of suspicion and the need for the careful use of diagnostic tools. CI - (c) Georg Thieme Verlag KG Stuttgart . New York. FAU - Meier, B AU - Meier B AD - Gastroenterologie, Klinikum Ludwigsburg, 71640 Ludwigsburg. benjamin.meier@kliniken-lb.de FAU - Schmidt, A AU - Schmidt A FAU - Kalmar, G AU - Kalmar G FAU - Caca, K AU - Caca K FAU - Wagner, D AU - Wagner D LA - eng PT - Journal Article DEP - 20130516 PL - Germany TA - Z Gastroenterol JT - Zeitschrift fur Gastroenterologie JID - 0033370 SB - IM MH - Abdominal Pain/*diagnosis/microbiology MH - Diagnosis, Differential MH - Female MH - HIV Infections/diagnosis/microbiology MH - Humans MH - Immune Reconstitution Inflammatory Syndrome/*diagnosis/*microbiology MH - Middle Aged MH - Mycobacterium Infections/*diagnosis/*microbiology MH - Tuberculosis/diagnosis/microbiology EDAT- 2013/05/18 06:00 MHDA- 2014/01/09 06:00 CRDT- 2013/05/18 06:00 PHST- 2013/05/18 06:00 [entrez] PHST- 2013/05/18 06:00 [pubmed] PHST- 2014/01/09 06:00 [medline] AID - 10.1055/s-0033-1335012 [doi] PST - ppublish SO - Z Gastroenterol. 2013 May;51(5):440-3. doi: 10.1055/s-0033-1335012. Epub 2013 May 16.