PMID- 23684466
OWN - NLM
STAT- MEDLINE
DCOM- 20131223
LR  - 20151119
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 781
DP  - 2013 Jun 5
TI  - Simultaneous determination of 19 triazine pesticides and degradation products in 
      processed cereal samples from Chinese total diet study by isotope dilution-high 
      performance liquid chromatography-linear ion trap mass spectrometry.
PG  - 63-71
LID - S0003-2670(13)00538-2 [pii]
LID - 10.1016/j.aca.2013.04.027 [doi]
AB  - A selective and sensitive isotope dilution-high performance liquid 
      chromatography-linear ion trap mass spectrometry (Isotope 
      Dilution-HPLC-LIT-MS(3)) method was developed for the simultaneous determination 
      of 19 triazine pesticides and their degradation products in processed cereal 
      samples from Chinese total diet study (TDS). The method integrated the addition 
      of isotope internal standards, liquid-liquid extraction (LLE), clean-up with MCX 
      solid-phase extraction (SPE) cartridges and HPLC-LIT-MS(3) analysis with selected 
      reaction monitoring (SRM) mode. Matrix-matched calibration curves showed good 
      linearity (R(2)>/=0.9940) verified by applying the Mandel's fitting test (p>0.087) 
      performed at the 95% confidence level. Decision limits (CCalphas) and detection 
      capabilities (CCbetas) of the 19 triazine pesticides and their degradation products 
      fell in the ranges of 0.0020-0.4200 mug kg(-1) and 0.0024-0.4500 mug kg(-1), 
      respectively. Recoveries ranged from 70.1% to 112.8%, with the relative standard 
      deviations (RSDs) ranging from 1.5% to 13.5%. Furthermore, the proposed method 
      was applied to analyzing the proposed cereal samples from the fourth Chinese TDS. 
      Eleven triazines were detected in six cereal samples with the concentrations 
      ranging from 0.013 to 0.987 mug kg(-1). This method can also be used for the 
      further determination of the triazines in other food group composites, and 
      ultimately served as a methodological foundation for assessing the triazines in 
      the average Chinese diet in the general population.
CI  - Copyright (c) 2013 Elsevier B.V. All rights reserved.
FAU - Li, Peng
AU  - Li P
AD  - College of Veterinary Medicine, China Agricultural University, Beijing 100193, 
      China.
FAU - Yang, Xin
AU  - Yang X
FAU - Miao, Hong
AU  - Miao H
FAU - Zhao, Yunfeng
AU  - Zhao Y
FAU - Liu, Wei
AU  - Liu W
FAU - Wu, Yongning
AU  - Wu Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130425
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
RN  - 0 (Pesticides)
RN  - 0 (Triazines)
SB  - IM
MH  - Calibration
MH  - China
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Diet
MH  - Edible Grain/*chemistry
MH  - Food Contamination/*analysis
MH  - Limit of Detection
MH  - Liquid-Liquid Extraction
MH  - Mass Spectrometry/*methods
MH  - Pesticides/*analysis
MH  - Radioisotope Dilution Technique
MH  - Reproducibility of Results
MH  - Solid Phase Extraction/methods
MH  - Triazines/*analysis
EDAT- 2013/05/21 06:00
MHDA- 2013/12/24 06:00
CRDT- 2013/05/21 06:00
PHST- 2012/12/16 00:00 [received]
PHST- 2013/04/04 00:00 [revised]
PHST- 2013/04/15 00:00 [accepted]
PHST- 2013/05/21 06:00 [entrez]
PHST- 2013/05/21 06:00 [pubmed]
PHST- 2013/12/24 06:00 [medline]
AID - S0003-2670(13)00538-2 [pii]
AID - 10.1016/j.aca.2013.04.027 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2013 Jun 5;781:63-71. doi: 10.1016/j.aca.2013.04.027. Epub 2013 
      Apr 25.