PMID- 23685364
OWN - NLM
STAT- MEDLINE
DCOM- 20131230
LR  - 20130603
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 458-460
DP  - 2013 Aug 1
TI  - Current concentrations, temporal trends and determinants of persistent organic 
      pollutants in breast milk of New Zealand women.
PG  - 399-407
LID - S0048-9697(13)00487-7 [pii]
LID - 10.1016/j.scitotenv.2013.04.055 [doi]
AB  - Breast milk samples of 39 first time mothers aged 20-30 were collected in 
      2007-2010 from rural and urban areas of New Zealand, following the fourth World 
      Health Organization coordinated survey protocol. Samples were individually 
      analysed for persistent organic pollutants (POPs) including dioxins and furans 
      (PCDD/Fs), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs) and 
      polybrominated diphenyl ethers (PBDEs). The lipid adjusted concentrations of 
      PCDD/Fs (mean toxic equivalent (TEQ): 3.54 pg/g) and PCBs (mean TEQ 1.29 pg/g) 
      were low in comparison to those reported for other countries, and concentrations 
      of dieldrin (10 ng/g) and p,p'-DDE (379 ng/g) and PBDEs were in the mid-range. 
      Breast milk concentrations of PCDD/F-TEQ, PCB-TEQ, dieldrin and p,p'-DDE were 
      significantly higher in rural compared to urban areas (+23%, 33%, 59%, and 44% 
      respectively), while concentrations of several PBDEs and lindane were higher in 
      urban areas. Concentrations of PCDD/Fs, PCBs and OCPs, but not PBDEs, increased 
      with age, and higher body mass index was associated with lower concentrations of 
      PCBs. Despite New Zealand's low body burdens of many chlorinated POPs in 
      comparison to other countries, breast milk concentrations continued to decrease 
      over time, with a decrease by half over the last 10 years for PCDD/F-TEQ (-40%), 
      PCB-TEQ (-54%) and OCPs -34 to -90%), indicating that regulatory measures 
      continue to have beneficial effects. Continued monitoring is needed particularly 
      for the brominated POPs for which little New Zealand specific data is available.
CI  - Copyright (c) 2013 Elsevier B.V. All rights reserved.
FAU - Mannetje, Andrea't
AU  - Mannetje A
AD  - Centre for Public Health Research, Massey University, PO Box 756, Wellington, New 
      Zealand. a.mannetje@massey.ac.nz
FAU - Coakley, Jonathan
AU  - Coakley J
FAU - Bridgen, Phil
AU  - Bridgen P
FAU - Brooks, Collin
AU  - Brooks C
FAU - Harrad, Stuart
AU  - Harrad S
FAU - Smith, Allan H
AU  - Smith AH
FAU - Pearce, Neil
AU  - Pearce N
FAU - Douwes, Jeroen
AU  - Douwes J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130515
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons)
SB  - IM
MH  - Age Factors
MH  - Body Burden
MH  - Body Mass Index
MH  - Environmental Monitoring/methods/*statistics & numerical data
MH  - Environmental Pollutants/*analysis
MH  - Female
MH  - Gas Chromatography-Mass Spectrometry
MH  - Humans
MH  - Hydrocarbons/*analysis
MH  - Milk, Human/*chemistry
MH  - New Zealand
MH  - Pregnancy
EDAT- 2013/05/21 06:00
MHDA- 2014/01/01 06:00
CRDT- 2013/05/21 06:00
PHST- 2013/01/30 00:00 [received]
PHST- 2013/04/18 00:00 [revised]
PHST- 2013/04/18 00:00 [accepted]
PHST- 2013/05/21 06:00 [entrez]
PHST- 2013/05/21 06:00 [pubmed]
PHST- 2014/01/01 06:00 [medline]
AID - S0048-9697(13)00487-7 [pii]
AID - 10.1016/j.scitotenv.2013.04.055 [doi]
PST - ppublish
SO  - Sci Total Environ. 2013 Aug 1;458-460:399-407. doi: 
      10.1016/j.scitotenv.2013.04.055. Epub 2013 May 15.