PMID- 23693094
OWN - NLM
STAT- MEDLINE
DCOM- 20140102
LR  - 20191210
IS  - 1873-4235 (Electronic)
IS  - 0956-5663 (Linking)
VI  - 48
DP  - 2013 Oct 15
TI  - Electrochemical detection of the amino-substituted naphthalene compounds based on 
      intercalative interaction with hairpin DNA by electrochemical impedance 
      spectroscopy.
PG  - 238-43
LID - S0956-5663(13)00272-8 [pii]
LID - 10.1016/j.bios.2013.04.008 [doi]
AB  - The amino-substituted naphthalene compounds, such as 1,8-diaminonaphthalene 
      (1,8-DANAP), 2,3-diaminonaphthalene (2,3-DANAP), 1,5-diaminonaphthalene 
      (1,5-DANAP), 1-naphthylamine (1-NAP) and 2-naphthylamine (2-NAP), were 
      investigated by electrochemical impedance spectroscopy (EIS), which was based on 
      the interaction with hairpin DNA immobilized on the gold electrodes. Upon hairpin 
      DNA interacting with the target chemicals, the charge transfer resistance (RCT) 
      of the hairpin DNA films was significantly decreased and the charge transfer 
      resistance change (DeltaR(CT)) decreased in a sequence of DeltaR(CT) (1,8-DANAP)>DeltaR(CT) 
      (2,3-DANAP)>DeltaR(CT) (1,5-DANAP)>DeltaR(CT) (1-NAP)>DeltaR(CT) (2-NAP). The DeltaR(CT) changes 
      were due to the difference in the binding constant (K(SV)) of the target 
      chemicals to DNA. In addition, the interaction mechanism was further explored 
      using 1,8-DANAP as a model analyte by fluorescence spectra, Raman spectroscopy, 
      differential pulse voltammetry (DPV) and EIS, correspondingly. The results 
      demonstrated that the amino-substituted naphthalene compounds intercalated into 
      "stem" appearing in the hairpin DNA. Moreover, the hairpin DNA sensor exhibited 
      high sensitivity to the amino-substituted naphthalene compounds with the 
      detection limit of nano-mole, and maintained high selectivity over other selected 
      environmental pollutants. Finally, the DNA sensor was challenged in natural water 
      sample with a recovery of 96-102%, which offered a platform for prospective 
      future development of a simple, rapid, sensitive and low-cost assay for the 
      detection of target aromatic amine pollutants.
CI  - Crown Copyright (c) 2013. Published by Elsevier B.V. All rights reserved.
FAU - Liang, Gang
AU  - Liang G
AD  - State Key Laboratory of Water Environment Simulation, School of Environment, 
      Beijing Normal University, Beijing 100875, PR China.
FAU - Li, Tao
AU  - Li T
FAU - Li, Xiaohong
AU  - Li X
FAU - Liu, Xinhui
AU  - Liu X
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20130415
PL  - England
TA  - Biosens Bioelectron
JT  - Biosensors & bioelectronics
JID - 9001289
RN  - 0 (Water Pollutants, Chemical)
RN  - 13PD3J52LK (1,5-diaminonaphthalene)
RN  - 2BNZ6BRS87 (2,3-diaminonaphthalene)
RN  - 9007-49-2 (DNA)
RN  - 9753I242R5 (1-Naphthylamine)
RN  - CKR7XL41N4 (2-Naphthylamine)
RN  - IKA7029YH9 (1,8-diaminonaphthalene)
SB  - IM
MH  - 1-Naphthylamine/*analysis
MH  - 2-Naphthylamine/analogs & derivatives/analysis
MH  - DNA/*chemistry
MH  - Dielectric Spectroscopy/*methods
MH  - Lakes/*analysis
MH  - Limit of Detection
MH  - Water Pollutants, Chemical/*analysis
EDAT- 2013/05/23 06:00
MHDA- 2014/01/03 06:00
CRDT- 2013/05/23 06:00
PHST- 2013/02/04 00:00 [received]
PHST- 2013/03/27 00:00 [revised]
PHST- 2013/04/03 00:00 [accepted]
PHST- 2013/05/23 06:00 [entrez]
PHST- 2013/05/23 06:00 [pubmed]
PHST- 2014/01/03 06:00 [medline]
AID - S0956-5663(13)00272-8 [pii]
AID - 10.1016/j.bios.2013.04.008 [doi]
PST - ppublish
SO  - Biosens Bioelectron. 2013 Oct 15;48:238-43. doi: 10.1016/j.bios.2013.04.008. Epub 
      2013 Apr 15.