PMID- 23708286
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20131227
LR  - 20130527
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 782
DP  - 2013 Jun 11
TI  - Separation of phthalates by cyclodextrin modified micellar electrokinetic 
      chromatography: quantitation in perfumes.
PG  - 67-74
LID - S0003-2670(13)00511-4 [pii]
LID - 10.1016/j.aca.2013.03.072 [doi]
AB  - A new CE method has been developed for the simultaneous separation of a group of 
      parent phthalates. Due to the neutral character of these compounds, the addition 
      of several bile salts as surfactants (sodium cholate (SC), sodium deoxycholate 
      (SDC), sodium taurodeoxycholate (STDC), sodium taurocholate (STC)) to the 
      separation buffer was explored showing the high potential of SDC as 
      pseudostationary phase. However, the resolution of all the phthalates was not 
      achieved when employing only this bile salt as additive, being necessary the 
      addition of neutral cyclodextrins (CD) and organic modifiers to the separation 
      media. The optimized cyclodextrin modified micellar electrokinetic chromatography 
      (CD-MEKC) method consisted of the employ of a background electrolyte (BGE) 
      containing 25 mM beta-CD-100 mM SDC in a 100 mM borate buffer (pH 8.5) with a 10% 
      (v/v) of acetonitrile, employing a voltage of 30 kV and a temperature of 25  degrees C. 
      This separation medium enabled the total resolution of eight compounds and the 
      partial resolution of two of the analytes, di-n-octyl phthalate (DNOP) and 
      diethyl hexyl phthalate (DEHP) (Rs~0.8), in only 12 min. The analytical 
      characteristics of the developed method were studied showing their suitability 
      for the determination of these compounds in commercial perfumes. In all the 
      analyzed perfumes the most common phthalate was diethyl phthalate (DEP) that 
      appeared in ten of the fifteen analyzed products. Also dimethyl phthalate (DMP), 
      diallyl phthalate (DAP), dicyclohexyl phthalate (DCP), and di-n-pentyl phthalate 
      (DNPP) were found in some of the analyzed samples.
CI  - Copyright (c) 2013 Elsevier B.V. All rights reserved.
FAU - Perez-Fernandez, Virginia
AU  - Perez-Fernandez V
AD  - Department of Analytical Chemistry, Faculty of Chemistry, University of Alcala, 
      Spain. virginia.perezf@uah.es
FAU - Gonzalez, Maria Jose
AU  - Gonzalez MJ
FAU - Garcia, Maria Angeles
AU  - Garcia MA
FAU - Marina, Maria Luisa
AU  - Marina ML
LA  - eng
PT  - Journal Article
DEP - 20130422
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
EDAT- 2013/05/28 06:00
MHDA- 2013/05/28 06:01
CRDT- 2013/05/28 06:00
PHST- 2012/12/27 00:00 [received]
PHST- 2013/02/26 00:00 [revised]
PHST- 2013/03/26 00:00 [accepted]
PHST- 2013/05/28 06:00 [entrez]
PHST- 2013/05/28 06:00 [pubmed]
PHST- 2013/05/28 06:01 [medline]
AID - S0003-2670(13)00511-4 [pii]
AID - 10.1016/j.aca.2013.03.072 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2013 Jun 11;782:67-74. doi: 10.1016/j.aca.2013.03.072. Epub 2013 
      Apr 22.