PMID- 23717011
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130530
LR  - 20211021
IS  - 1013-9087 (Print)
IS  - 2005-3894 (Electronic)
IS  - 1013-9087 (Linking)
VI  - 25
IP  - 2
DP  - 2013 May
TI  - Food hypersensitivity in patients with childhood atopic dermatitis in Korea.
PG  - 196-202
LID - 10.5021/ad.2013.25.2.196 [doi]
AB  - BACKGROUND: It is well known that atopic dermatitis (AD) is related to food 
      hypersensitivity, although its prevalence varies among several studies according 
      to age group, severity, country, survey time, and test method. OBJECTIVE: To 
      examine the prevalence and status of food hypersensitivity among childhood AD 
      patients in Korea. METHODS: A total of 95 patients were enrolled in the study. 
      The history of food hypersensitivity was collected by interviews. The severity of 
      AD was evaluated by eczema area and severity index (EASI). We took blood samples 
      to measure serum total and food-specific immunoglobulin E (IgE) levels. Based on 
      the histories and serum IgE levels, open oral food challenge (OFC) testing was 
      performed to confirm food hypersensitivity. RESULTS: Forty-two (44.2%) of the 95 
      AD patients had histories of food hypersensitivity. They reported that the most 
      common suspicious foods were egg (n=13, 13.7%), pork (n=9, 9.5%) and cow milk 
      (n=8, 8.4%). The mean EASI score was 16.05+/-9.76. Thirty-nine (41.1%) of the 95 
      patients showed elevated serum food-specific IgE levels. The specific IgE levels 
      were elevated for egg (n=17, 17.9%), milk (n=12, 12.6%), peanut (n=10, 10.5%) and 
      wheat (n=8, 8.4%). Fifty-one (53.8%) of 95 patients underwent open OFC, and only 
      7 (13.7%) of these patients showed positive reactions. CONCLUSION: The overall 
      prevalence of food hypersensitivity in patients with childhood AD in Korea was 
      8.3% (7/84). The most common foods causing food hypersensitivity were egg and 
      milk. Among the foods causing hypersensitivity, AD patients in Korea often 
      underestimated peanut, while they overestimated pork.
FAU - Kim, Hye One
AU  - Kim HO
AD  - Department of Dermatology, Kangnam Sacred Heart Hospital, College of Medicine, 
      Hallym University, Seoul, Korea.
FAU - Cho, Soo Ick
AU  - Cho SI
FAU - Kim, Jin Hye
AU  - Kim JH
FAU - Chung, Bo Young
AU  - Chung BY
FAU - Cho, Hee Jin
AU  - Cho HJ
FAU - Park, Chun Wook
AU  - Park CW
FAU - Lee, Cheol Heon
AU  - Lee CH
LA  - eng
PT  - Journal Article
DEP - 20130510
PL  - Korea (South)
TA  - Ann Dermatol
JT  - Annals of dermatology
JID - 8916577
PMC - PMC3662913
OTO - NOTNLM
OT  - Atopic dermatitis
OT  - Food allergy
OT  - Food hypersensitivity
OT  - Korean
OT  - Oral food challenge
EDAT- 2013/05/30 06:00
MHDA- 2013/05/30 06:01
PMCR- 2013/05/01
CRDT- 2013/05/30 06:00
PHST- 2012/02/09 00:00 [received]
PHST- 2012/05/02 00:00 [revised]
PHST- 2012/05/03 00:00 [accepted]
PHST- 2013/05/30 06:00 [entrez]
PHST- 2013/05/30 06:00 [pubmed]
PHST- 2013/05/30 06:01 [medline]
PHST- 2013/05/01 00:00 [pmc-release]
AID - 10.5021/ad.2013.25.2.196 [doi]
PST - ppublish
SO  - Ann Dermatol. 2013 May;25(2):196-202. doi: 10.5021/ad.2013.25.2.196. Epub 2013 
      May 10.