PMID- 23718236 OWN - NLM STAT- MEDLINE DCOM- 20140207 LR - 20160704 IS - 1938-2359 (Electronic) IS - 0090-4481 (Linking) VI - 42 IP - 6 DP - 2013 Jun 1 TI - Epidemiology of childhood food allergy. PG - 91-5 LID - 10.3928/00904481-20130522-08 [doi] AB - Food allergy is a public health problem that affects nearly 6 million children in the United States. The extent to which children, families, and communities live with food allergies varies as much as the range of clinical symptoms associated with the disease itself. Food allergy is defined as the reproducible adverse event that elicits a pathologic immunoglobulin E (IgE)-mediated or non-IgE-mediated reaction. Once an allergic child ingests a specific food allergen, the reaction can result in clinical symptoms ranging from mild hives to life-threatening anaphylaxis.Not surprisingly, food allergies have been shown to limit social interactions and impair children's quality of life due to the ubiquity of food where children live, learn, and play. To ensure the safety of our children, the development of sound policy, clinical practice, and health programs must be informed by current research characterizing childhood food allergy at the population level. To set the stage for understanding the current evidence base, this article reviews: 1) epidemiology of childhood food allergy; 2) severity of symptoms; 3) geographic distribution of childhood food allergy; 4) tolerance; 5) economic impact of childhood food allergy; and 6) future directions in childhood food allergy epidemiological research. CI - Copyright 2013, SLACK Incorporated. FAU - Dyer, Ashley A AU - Dyer AA AD - Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, 750 North Lake Shore Drive, 10th Floor, Chicago, IL 60611, USA. ashley.dyer@northwestern.edu FAU - Gupta, Ruchi AU - Gupta R LA - eng PT - Journal Article PT - Review PL - United States TA - Pediatr Ann JT - Pediatric annals JID - 0356657 SB - IM MH - Adolescent MH - Child MH - Child, Preschool MH - Cost of Illness MH - Disease Progression MH - Food Hypersensitivity/economics/*epidemiology MH - Health Care Costs MH - Humans MH - Infant MH - Infant, Newborn MH - Prevalence MH - Severity of Illness Index MH - United States/epidemiology EDAT- 2013/05/31 06:00 MHDA- 2014/02/08 06:00 CRDT- 2013/05/31 06:00 PHST- 2013/05/31 06:00 [entrez] PHST- 2013/05/31 06:00 [pubmed] PHST- 2014/02/08 06:00 [medline] AID - 10.3928/00904481-20130522-08 [doi] PST - ppublish SO - Pediatr Ann. 2013 Jun 1;42(6):91-5. doi: 10.3928/00904481-20130522-08.