PMID- 23724221
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130603
LR  - 20211021
IS  - 2090-5521 (Print)
IS  - 2090-553X (Electronic)
IS  - 2090-553X (Linking)
VI  - 2011
DP  - 2011
TI  - Predictors of Serum Total IgE in a Random Sample of 7-17 Year Old Children.
PG  - 169859
LID - 10.5402/2011/169859 [doi]
LID - 169859
AB  - Background. There is little knowledge of the causes for raised serum total 
      immunoglobulin E (IgE) in children. We investigated the association between 
      perinatal, socioeconomic, demographic, clinical, paraclinical, and early life 
      factors, and total serum IgE. Methods. In a random sample of 7-17 year old 
      children, data on possible risk factors were collected using a questionnaire and 
      total serum IgE was measured in venous blood. Airway responsiveness to inhaled 
      histamine was measured and skin prick tests were performed using common 
      aeroallergens. Data was analysed using linear regression. Results. Positive skin 
      prick test (P < .001), airway hyperresponsiveness (P = .003), atopic dermatitis 
      (P = .046), and parental predisposition to allergy (P = .047) showed a 
      significant relation to serum total IgE levels. There was no association of 
      smoking to serum total IgE. Conclusions. This study showed a strong positive 
      relationship between markers of the atopic syndrome and serum total IgE levels in 
      children. In contrast to some earlier studies, we did not find a significant 
      relation between smoking status and IgE.
FAU - Stromgaard, Sofie
AU  - Stromgaard S
AD  - Department of Respiratory Medicine, Bispebjerg Hospital, 2400 Copenhagen, 
      Denmark.
FAU - Thomsen, Simon Francis
AU  - Thomsen SF
FAU - Fenger, Mogens
AU  - Fenger M
FAU - Backer, Vibeke
AU  - Backer V
LA  - eng
PT  - Journal Article
DEP - 20110531
PL  - United States
TA  - ISRN Allergy
JT  - ISRN allergy
JID - 101605568
PMC - PMC3658556
EDAT- 2011/01/01 00:00
MHDA- 2011/01/01 00:01
PMCR- 2011/05/31
CRDT- 2013/06/01 06:00
PHST- 2011/03/07 00:00 [received]
PHST- 2011/04/11 00:00 [accepted]
PHST- 2013/06/01 06:00 [entrez]
PHST- 2011/01/01 00:00 [pubmed]
PHST- 2011/01/01 00:01 [medline]
PHST- 2011/05/31 00:00 [pmc-release]
AID - 10.5402/2011/169859 [doi]
PST - epublish
SO  - ISRN Allergy. 2011 May 31;2011:169859. doi: 10.5402/2011/169859. Print 2011.