PMID- 23734859 OWN - NLM STAT- MEDLINE DCOM- 20140328 LR - 20211021 IS - 1365-2915 (Electronic) IS - 0269-283X (Print) IS - 0269-283X (Linking) VI - 27 IP - 3 DP - 2013 Sep TI - Chironomid midge sensitization in sewage workers: case study. PG - 346-8 LID - 10.1111/j.1365-2915.2012.01058.x [doi] AB - Non-biting chironomid midges (Diptera: Chironomidae) may cause sensitization and allergic reactions in humans and have recently been identified as a potential health problem in Swedish municipal sewage treatment plants. To investigate, on a pilot scale, the allergenic potential of chironomids in sewage workers, all workers (n = 8) at a sewage treatment plant and local controls (n = 16) completed a symptom questionnaire, underwent measurement of the fraction of nitric oxide in exhaled air, spirometry, and provided serum samples for the determination of atopy status and the prevalence of specific immunoglobulin E (IgE) antibodies against Chironomus thummi (Chi t) using a commercial fluorescence enzyme immunoassay (FEIA). Three sewage workers (38%) but no controls (0%) were FEIA positive for C. thummi-specific IgE antibodies (P < 0.05). No other health-related findings were significantly different between the groups. The study suggested that occupational exposure to Chironomids may cause sensitization with circulating IgE-antibodies in sewage workers. CI - (c) 2013 The Royal Entomological Society. FAU - Selden, A I AU - Selden AI AD - Department of Occupational and Environmental Medicine, Orebro University Hospital, Orebro, Sweden. anders.selden@orebroll.se FAU - Calo, A AU - Calo A FAU - Molleby, G AU - Molleby G FAU - Hultgren, O AU - Hultgren O LA - eng PT - Journal Article DEP - 20130605 PL - England TA - Med Vet Entomol JT - Medical and veterinary entomology JID - 8708682 RN - 0 (Allergens) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - Adult MH - Allergens/*immunology MH - Animals MH - Case-Control Studies MH - Chironomidae/*immunology MH - Female MH - Fluoroimmunoassay MH - Forced Expiratory Volume MH - Humans MH - Hypersensitivity, Immediate/*immunology MH - Immunoglobulin E/blood MH - Male MH - Middle Aged MH - Occupational Diseases/*immunology MH - Spirometry MH - Vital Capacity MH - *Waste Disposal, Fluid PMC - PMC3842108 OTO - NOTNLM OT - Chironomus thummi OT - IgE OT - fluorescence enzyme immunoassay OT - sensitization OT - sewage treatment OT - sewage workers EDAT- 2013/06/06 06:00 MHDA- 2014/03/29 06:00 CRDT- 2013/06/06 06:00 PHST- 2013/06/06 06:00 [entrez] PHST- 2013/06/06 06:00 [pubmed] PHST- 2014/03/29 06:00 [medline] AID - 10.1111/j.1365-2915.2012.01058.x [doi] PST - ppublish SO - Med Vet Entomol. 2013 Sep;27(3):346-8. doi: 10.1111/j.1365-2915.2012.01058.x. Epub 2013 Jun 5.