PMID- 23736042
OWN - NLM
STAT- MEDLINE
DCOM- 20140305
LR  - 20160603
IS  - 1421-9751 (Electronic)
IS  - 0008-6312 (Linking)
VI  - 125
IP  - 3
DP  - 2013
TI  - Surgical RF ablation of atrial fibrillation in patients undergoing mitral valve 
      repair for Barlow disease.
PG  - 141-5
LID - 10.1159/000348565 [doi]
AB  - OBJECTIVES: At present, limited experience exists on the treatment of atrial 
      fibrillation (AF) in patients undergoing mitral valve repair (MVR) for Barlow 
      disease. The aim of this investigation was to prospectively evaluate the 
      radiofrequency ablation of AF in patients undergoing MVR for severe regurgitation 
      due to Barlow disease. METHODS: From January 1, 2007 to December 31, 2010, out of 
      85 consecutive patients with Barlow disease, 27 with AF underwent RF ablation 
      associated with MVR. They were examined every 4 months in the first year after 
      surgery and thereafter twice yearly. RESULTS: At follow-up, AF was observed in 
      4/25 (16.0%). NYHA (New York Heart Association) functional class improved 
      significantly, with no patients in class III or IV (before surgery, 81.5% had 
      been). Otherwise, among 58 patients in sinus rhythm, 6 (11%) developed AF during 
      follow-up. No clinical or echocardiographic predictive factor was found in this 
      subgroup. CONCLUSIONS: Results from our investigation suggest that radiofrequency 
      ablation of AF in patients with Barlow disease undergoing MVR for severe 
      regurgitation is effective and should be considered in every patient with Barlow 
      disease and AF undergoing valve surgical repair.
CI  - Copyright (c) 2013 S. Karger AG, Basel.
FAU - Rostagno, Carlo
AU  - Rostagno C
AD  - Dipartimento Area Critica Universita degli Studi di Firenze, Florence, Italy. 
      carlo.rostagno@unifi.it
FAU - Droandi, G
AU  - Droandi G
FAU - Gelsomino, S
AU  - Gelsomino S
FAU - Carone, E
AU  - Carone E
FAU - Gensini, G F
AU  - Gensini GF
FAU - Stefano, P L
AU  - Stefano PL
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
DEP - 20130530
PL  - Switzerland
TA  - Cardiology
JT  - Cardiology
JID - 1266406
RN  - Barlow syndrome
SB  - IM
MH  - *Ablation Techniques
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Atrial Fibrillation/etiology/*surgery
MH  - Female
MH  - Genetic Diseases, X-Linked/complications/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/surgery
MH  - Mitral Valve Annuloplasty
MH  - Mitral Valve Prolapse/complications/*surgery
MH  - Prospective Studies
EDAT- 2013/06/06 06:00
MHDA- 2014/03/07 06:00
CRDT- 2013/06/06 06:00
PHST- 2012/12/12 00:00 [received]
PHST- 2013/01/28 00:00 [accepted]
PHST- 2013/06/06 06:00 [entrez]
PHST- 2013/06/06 06:00 [pubmed]
PHST- 2014/03/07 06:00 [medline]
AID - 000348565 [pii]
AID - 10.1159/000348565 [doi]
PST - ppublish
SO  - Cardiology. 2013;125(3):141-5. doi: 10.1159/000348565. Epub 2013 May 30.