PMID- 23741567
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20130607
LR  - 20220419
IS  - 2005-6419 (Print)
IS  - 2005-7563 (Electronic)
IS  - 2005-6419 (Linking)
VI  - 64
IP  - 5
DP  - 2013 May
TI  - Effect of stellate ganglion block on laryngopharyngeal reflux disease.
PG  - 439-42
LID - 10.4097/kjae.2013.64.5.439 [doi]
AB  - BACKGROUND: Laryngopharyngeal reflux (LPR) disease has many symptoms such as 
      globus pharyngeus, excessive throat clearing and hoarseness. The aim of this 
      study was to investigate the effect of stellate ganglion block (SGB) in addition 
      to proton pump inhibitors (PPI) on LPR. METHODS: Fifty patients complaining of 
      more than 3 typical LPR symptoms for over 3 months were enrolled in the study. 
      The P group took PPI for 8 weeks. The SP group took PPI and interwent a series of 
      8 SGB procedure once a week during the period of treatment. The blocks were 
      performed one at a time unilaterally on the right and left stellate ganglions by 
      injecting 1% mepivacaine 6 ml. We evaluated the reflux symptom index (RSI) before 
      treatment and following 4 weeks and 8 weeks of treatment in both groups. RESULTS: 
      After 4 weeks of treatment, the RSI of the P group decreased, but not 
      significantly, to 16.6 +/- 6.8 compared with the baseline value of 19.2 +/- 2.7 (P = 
      0.093), whereas the RSI of the SP group decreased significantly to 9.8 +/- 3.3 
      compared with the baseline value of 19.0 +/- 4.7 (P = 0.000). After 8 weeks of 
      treatment, the RSI of the P group decreased significantly to 13.7 +/- 6.7 (P = 
      0.001) and the RSI of the SP group also decreased significantly to 7.7 +/- 3.4 (P = 
      0.000). There were significant differences in the RSI between the two groups 
      after 4 weeks (P = 0.000) and 8 weeks (P = 0.001) of treatment. CONCLUSIONS: The 
      symptoms of LPR improved earlier when PPI therapy was combined with SGB compared 
      with PPI therapy alone.
FAU - Chung, Ji Won
AU  - Chung JW
AD  - Department of Anesthesiology and Pain Medicine, Soonchunhyang University 
      Hospital, College of Medicine, Soonchunhyang University, Cheonan, Korea.
FAU - Chun, Hye Jung
AU  - Chun HJ
FAU - Lee, Mi Soon
AU  - Lee MS
FAU - Ahn, Ki Ryang
AU  - Ahn KR
FAU - Kim, Chun Sook
AU  - Kim CS
FAU - Kang, Kyu Sik
AU  - Kang KS
FAU - Yoo, Sie Hyeon
AU  - Yoo SH
FAU - Chung, Jin Hun
AU  - Chung JH
FAU - Kim, Nan-Seol
AU  - Kim NS
FAU - Seo, Yong Han
AU  - Seo YH
FAU - Gong, Hyung Youn
AU  - Gong HY
FAU - Lee, Yong Man
AU  - Lee YM
LA  - eng
PT  - Journal Article
DEP - 20130524
PL  - Korea (South)
TA  - Korean J Anesthesiol
JT  - Korean journal of anesthesiology
JID - 101502451
PMC - PMC3668106
OTO - NOTNLM
OT  - Laryngopharyngeal reflux
OT  - Proton pump inhibitors
OT  - Stellate ganglion block
EDAT- 2013/06/07 06:00
MHDA- 2013/06/07 06:01
PMCR- 2013/05/01
CRDT- 2013/06/07 06:00
PHST- 2012/05/07 00:00 [received]
PHST- 2012/11/11 00:00 [revised]
PHST- 2012/11/28 00:00 [accepted]
PHST- 2013/06/07 06:00 [entrez]
PHST- 2013/06/07 06:00 [pubmed]
PHST- 2013/06/07 06:01 [medline]
PHST- 2013/05/01 00:00 [pmc-release]
AID - 10.4097/kjae.2013.64.5.439 [doi]
PST - ppublish
SO  - Korean J Anesthesiol. 2013 May;64(5):439-42. doi: 10.4097/kjae.2013.64.5.439. 
      Epub 2013 May 24.